Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1806 Cabozantinib
0.031623
VEGFR2/MET
RTK
 1.0527 -0.00144
HCC1806 Cabozantinib
0.1
VEGFR2/MET
RTK
 1.0055 0.00116
HCC1806 Cabozantinib
0.31623
VEGFR2/MET
RTK
 1.0807 -0.00645
HCC1806 Cabozantinib
1.0
VEGFR2/MET
RTK
 1.0440 0.00245
HCC1806 Cabozantinib
3.1623
VEGFR2/MET
RTK
 1.1649 -0.01665
HCC1806 Cabozantinib
10.0
VEGFR2/MET
RTK
 0.6905 0.06098
Hs 578T Abemaciclib
0.001
CDK4/6
Cell cycle
 0.9336 0.00408
Hs 578T Abemaciclib
0.0031623
CDK4/6
Cell cycle
 0.7910 0.00854
Hs 578T Abemaciclib
0.01
CDK4/6
Cell cycle
 0.7172 0.02597
Hs 578T Abemaciclib
0.031623
CDK4/6
Cell cycle
 0.5384 0.04538
Hs 578T Abemaciclib
0.1
CDK4/6
Cell cycle
 0.4237 0.07522
Hs 578T Abemaciclib
0.31623
CDK4/6
Cell cycle
 0.2917 0.09522
Hs 578T Abemaciclib
1.0
CDK4/6
Cell cycle
 0.2262 0.17140
Hs 578T Abemaciclib
3.1623
CDK4/6
Cell cycle
 -0.2382 0.50027
Hs 578T Abemaciclib
10.0
CDK4/6
Cell cycle
 -0.5825 0.84364
Hs 578T Palbociclib
0.00031623
CDK4/6
Cell cycle
 1.0302 -0.00544
Hs 578T Palbociclib
0.001
CDK4/6
Cell cycle
 0.9864 0.00720
Hs 578T Palbociclib
0.0031623
CDK4/6
Cell cycle
 0.9286 0.00241
Hs 578T Palbociclib
0.01
CDK4/6
Cell cycle
 0.7655 0.01515
Hs 578T Palbociclib
0.031623
CDK4/6
Cell cycle
 0.6661 0.01800
Hs 578T Palbociclib
0.1
CDK4/6
Cell cycle
 0.5601 0.04580
Hs 578T Palbociclib
0.31623
CDK4/6
Cell cycle
 0.4560 0.05357
Hs 578T Palbociclib
1.0
CDK4/6
Cell cycle
 0.4135 0.07460
Hs 578T Palbociclib
3.1623
CDK4/6
Cell cycle
 0.3049 0.11532
Hs 578T AZD7762
0.001
CHK1/2
Cell cycle
 1.0689 0.00507