Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
HCC1806 | Cisplatin | 0.31623 | Chemo | Chemotherapy | 0.7090 | 0.01990 |
HCC1806 | Cisplatin | 1.0 | Chemo | Chemotherapy | 0.4865 | 0.10898 |
HCC1806 | Cisplatin | 3.1623 | Chemo | Chemotherapy | -0.1138 | 0.28875 |
HCC1806 | Cisplatin | 10.0 | Chemo | Chemotherapy | -0.3648 | 0.50046 |
HCC1806 | Doxorubicin | 0.00031623 | Chemo | Chemotherapy | 0.9295 | 0.00552 |
HCC1806 | Doxorubicin | 0.001 | Chemo | Chemotherapy | 0.9949 | 0.00116 |
HCC1806 | Doxorubicin | 0.0031623 | Chemo | Chemotherapy | 0.9411 | 0.01376 |
HCC1806 | Doxorubicin | 0.01 | Chemo | Chemotherapy | 0.6358 | 0.10489 |
HCC1806 | Doxorubicin | 0.031623 | Chemo | Chemotherapy | 0.2074 | 0.21696 |
HCC1806 | Doxorubicin | 0.1 | Chemo | Chemotherapy | 0.0325 | 0.24860 |
HCC1806 | Doxorubicin | 0.31623 | Chemo | Chemotherapy | -0.0087 | 0.27447 |
HCC1806 | Doxorubicin | 1.0 | Chemo | Chemotherapy | -0.1301 | 0.33133 |
HCC1806 | Doxorubicin | 3.1623 | Chemo | Chemotherapy | -0.3241 | 0.57687 |
HCC1806 | Taxol | 0.0001 | Chemo | Chemotherapy | 0.7362 | 0.03761 |
HCC1806 | Taxol | 0.00031623 | Chemo | Chemotherapy | 1.0636 | -0.00191 |
HCC1806 | Taxol | 0.001 | Chemo | Chemotherapy | 0.6890 | 0.09120 |
HCC1806 | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.0392 | 0.34787 |
HCC1806 | Taxol | 0.01 | Chemo | Chemotherapy | -0.1493 | 0.46357 |
HCC1806 | Taxol | 0.031623 | Chemo | Chemotherapy | -0.1770 | 0.52601 |
HCC1806 | Taxol | 0.1 | Chemo | Chemotherapy | -0.2222 | 0.55080 |
HCC1806 | Taxol | 0.31623 | Chemo | Chemotherapy | -0.2113 | 0.55998 |
HCC1806 | Taxol | 1.0 | Chemo | Chemotherapy | -0.2088 | 0.56878 |
HCC1806 | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.8402 | 0.01224 |
HCC1806 | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.8148 | 0.03520 |
HCC1806 | Topotecan | 0.01 | Topo I | Chemotherapy | 0.1002 | 0.20611 |