Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HME1 Saracatinib
0.001
SRC
MAPK/nRTK
 1.0489 0.00002
HME1 Saracatinib
0.0031623
SRC
MAPK/nRTK
 1.1354 0.00082
HME1 Saracatinib
0.01
SRC
MAPK/nRTK
 1.0882 0.00000
HME1 Saracatinib
0.031623
SRC
MAPK/nRTK
 1.1144 -0.00028
HME1 Saracatinib
0.1
SRC
MAPK/nRTK
 1.1314 0.00515
HME1 Saracatinib
0.31623
SRC
MAPK/nRTK
 1.1211 0.00839
HME1 Saracatinib
1.0
SRC
MAPK/nRTK
 1.0926 0.00022
HME1 Saracatinib
3.1623
SRC
MAPK/nRTK
 0.9252 -0.00464
HME1 Saracatinib
10.0
SRC
MAPK/nRTK
 0.4596 0.02699
HME1 ABT-737
0.001
Bcl2/XL
Misc
 1.0697 -0.00214
HME1 ABT-737
0.0031623
Bcl2/XL
Misc
 1.0591 0.00006
HME1 ABT-737
0.01
Bcl2/XL
Misc
 1.0844 0.00207
HME1 ABT-737
0.031623
Bcl2/XL
Misc
 1.0662 0.01157
HME1 ABT-737
0.1
Bcl2/XL
Misc
 1.0468 0.02011
HME1 ABT-737
0.31623
Bcl2/XL
Misc
 0.9838 0.02550
HME1 ABT-737
1.0
Bcl2/XL
Misc
 0.8158 0.04436
HME1 ABT-737
3.1623
Bcl2/XL
Misc
 0.4949 0.08784
HME1 ABT-737
10.0
Bcl2/XL
Misc
 0.5330 0.08315
HME1 Vorinostat
0.001
HDAC
Misc
 1.0348 -0.00386
HME1 Vorinostat
0.0031623
HDAC
Misc
 1.0080 0.00069
HME1 Vorinostat
0.01
HDAC
Misc
 1.0241 -0.00170
HME1 Vorinostat
0.031623
HDAC
Misc
 1.0031 0.00074
HME1 Vorinostat
0.1
HDAC
Misc
 0.9346 0.00431
HME1 Vorinostat
0.31623
HDAC
Misc
 0.9503 0.00251
HME1 Vorinostat
1.0
HDAC
Misc
 0.8349 0.00192