Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HME1 Vorinostat
3.1623
HDAC
Misc
 0.4769 0.02514
HME1 Vorinostat
10.0
HDAC
Misc
 0.0551 0.10485
HME1 Luminespib
0.0001
HSP90
Misc
 1.0484 0.00031
HME1 Luminespib
0.00031623
HSP90
Misc
 1.1089 0.00465
HME1 Luminespib
0.001
HSP90
Misc
 1.1215 0.00534
HME1 Luminespib
0.0031623
HSP90
Misc
 1.0870 0.00358
HME1 Luminespib
0.01
HSP90
Misc
 0.2421 0.11891
HME1 Luminespib
0.031623
HSP90
Misc
 -0.3219 0.66040
HME1 Luminespib
0.1
HSP90
Misc
 -0.3361 0.67249
HME1 Luminespib
0.31623
HSP90
Misc
 -0.3346 0.67063
HME1 Luminespib
1.0
HSP90
Misc
 -0.3187 0.68224
HME1 A-1210477
0.001
Mcl-1
Misc
 1.0214 -0.00243
HME1 A-1210477
0.0031623
Mcl-1
Misc
 1.0217 -0.00195
HME1 A-1210477
0.01
Mcl-1
Misc
 1.0162 -0.00300
HME1 A-1210477
0.031623
Mcl-1
Misc
 1.0255 -0.00279
HME1 A-1210477
0.1
Mcl-1
Misc
 0.9827 -0.00218
HME1 A-1210477
0.31623
Mcl-1
Misc
 0.9266 -0.00360
HME1 A-1210477
1.0
Mcl-1
Misc
 0.4068 0.08475
HME1 A-1210477
3.1623
Mcl-1
Misc
 -0.3871 0.56207
HME1 A-1210477
10.0
Mcl-1
Misc
 -0.4222 0.62397
HME1 Olaparib
0.001
PARP
Misc
 1.0220 -0.00435
HME1 Olaparib
0.0031623
PARP
Misc
 1.0354 -0.00198
HME1 Olaparib
0.01
PARP
Misc
 1.0427 -0.00612
HME1 Olaparib
0.031623
PARP
Misc
 1.0329 0.00061
HME1 Olaparib
0.1
PARP
Misc
 1.0407 -0.00372