Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HME1 Olaparib
0.31623
PARP
Misc
 1.0060 -0.00631
HME1 Olaparib
1.0
PARP
Misc
 0.9750 -0.00413
HME1 Olaparib
3.1623
PARP
Misc
 0.8543 0.00539
HME1 Olaparib
10.0
PARP
Misc
 0.5911 0.01243
HME1 Bleomycin
0.0010833
Radiation
Misc
 0.9826 -0.00155
HME1 Bleomycin
0.0033333
Radiation
Misc
 0.9476 0.00118
HME1 Bleomycin
0.01
Radiation
Misc
 0.8668 0.00491
HME1 Bleomycin
0.031667
Radiation
Misc
 0.8038 0.01219
HME1 Bleomycin
0.1
Radiation
Misc
 0.7595 0.02491
HME1 Bleomycin
0.31623
Radiation
Misc
 0.3925 0.10661
HME1 Bleomycin
1.0
Radiation
Misc
 0.0645 0.20679
HME1 Bleomycin
3.1623
Radiation
Misc
 -0.0835 0.27521
HME1 Bleomycin
10.0
Radiation
Misc
 -0.1105 0.33528
HME1 Ipatasertib
0.001
AKT
PI3K/mTOR
 1.0387 -0.00145
HME1 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0755 -0.00146
HME1 Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0891 0.00071
HME1 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0779 0.00343
HME1 Ipatasertib
0.1
AKT
PI3K/mTOR
 1.0320 0.00354
HME1 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.9815 0.00658
HME1 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.9096 0.00864
HME1 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.7982 0.02206
HME1 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.6353 0.02868
HME1 Alpelisib
0.001
PI3Ka
PI3K/mTOR
 0.9241 0.00556
HME1 Alpelisib
0.0031623
PI3Ka
PI3K/mTOR
 0.9769 0.00365
HME1 Alpelisib
0.01
PI3Ka
PI3K/mTOR
 1.0045 -0.00054