Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| SUM1315MO2 | Cisplatin | 3.1623 | Chemo | Chemotherapy | 0.3176 | 0.14509 |
| SUM1315MO2 | Cisplatin | 10.0 | Chemo | Chemotherapy | 0.2028 | 0.23776 |
| SUM1315MO2 | Doxorubicin | 0.00031623 | Chemo | Chemotherapy | 0.9250 | 0.01794 |
| SUM1315MO2 | Doxorubicin | 0.001 | Chemo | Chemotherapy | 0.9638 | 0.00498 |
| SUM1315MO2 | Doxorubicin | 0.0031623 | Chemo | Chemotherapy | 0.9521 | 0.02241 |
| SUM1315MO2 | Doxorubicin | 0.01 | Chemo | Chemotherapy | 0.7752 | 0.05037 |
| SUM1315MO2 | Doxorubicin | 0.031623 | Chemo | Chemotherapy | 0.2699 | 0.20353 |
| SUM1315MO2 | Doxorubicin | 0.1 | Chemo | Chemotherapy | 0.1337 | 0.20540 |
| SUM1315MO2 | Doxorubicin | 0.31623 | Chemo | Chemotherapy | 0.1933 | 0.20977 |
| SUM1315MO2 | Doxorubicin | 1.0 | Chemo | Chemotherapy | 0.1753 | 0.23142 |
| SUM1315MO2 | Doxorubicin | 3.1623 | Chemo | Chemotherapy | -0.0635 | 0.24619 |
| SUM1315MO2 | Taxol | 0.0001 | Chemo | Chemotherapy | 1.0258 | 0.01087 |
| SUM1315MO2 | Taxol | 0.00031623 | Chemo | Chemotherapy | 1.0435 | 0.01056 |
| SUM1315MO2 | Taxol | 0.001 | Chemo | Chemotherapy | 0.8773 | 0.06705 |
| SUM1315MO2 | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.3379 | 0.27957 |
| SUM1315MO2 | Taxol | 0.01 | Chemo | Chemotherapy | -0.1765 | 0.42783 |
| SUM1315MO2 | Taxol | 0.031623 | Chemo | Chemotherapy | -0.1802 | 0.42356 |
| SUM1315MO2 | Taxol | 0.1 | Chemo | Chemotherapy | -0.3052 | 0.48467 |
| SUM1315MO2 | Taxol | 0.31623 | Chemo | Chemotherapy | -0.2918 | 0.47769 |
| SUM1315MO2 | Taxol | 1.0 | Chemo | Chemotherapy | -0.3258 | 0.46429 |
| SUM1315MO2 | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.8689 | 0.01114 |
| SUM1315MO2 | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.6181 | 0.06747 |
| SUM1315MO2 | Topotecan | 0.01 | Topo I | Chemotherapy | 0.4048 | 0.18409 |
| SUM1315MO2 | Topotecan | 0.031667 | Topo I | Chemotherapy | 0.2827 | 0.22120 |
| SUM1315MO2 | Topotecan | 0.1 | Topo I | Chemotherapy | 0.3316 | 0.22251 |