Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
SUM1315MO2 Cabozantinib
0.31623
VEGFR2/MET
RTK
 0.9829 0.00794
SUM1315MO2 Cabozantinib
1.0
VEGFR2/MET
RTK
 0.8627 0.02206
SUM1315MO2 Cabozantinib
3.1623
VEGFR2/MET
RTK
 0.6423 0.02120
SUM1315MO2 Cabozantinib
10.0
VEGFR2/MET
RTK
 0.1095 0.07775
SUM159PT Abemaciclib
0.001
CDK4/6
Cell cycle
 0.9807 -0.00067
SUM159PT Abemaciclib
0.0031623
CDK4/6
Cell cycle
 0.9550 -0.00302
SUM159PT Abemaciclib
0.01
CDK4/6
Cell cycle
 0.8839 -0.00242
SUM159PT Abemaciclib
0.031623
CDK4/6
Cell cycle
 0.7491 -0.00288
SUM159PT Abemaciclib
0.1
CDK4/6
Cell cycle
 0.5999 0.00520
SUM159PT Abemaciclib
0.31623
CDK4/6
Cell cycle
 0.4511 0.00754
SUM159PT Abemaciclib
1.0
CDK4/6
Cell cycle
 0.2523 0.01021
SUM159PT Abemaciclib
3.1623
CDK4/6
Cell cycle
 0.1842 0.01555
SUM159PT Abemaciclib
10.0
CDK4/6
Cell cycle
 -0.4677 0.88367
SUM159PT Palbociclib
0.00031623
CDK4/6
Cell cycle
 0.9978 0.00047
SUM159PT Palbociclib
0.001
CDK4/6
Cell cycle
 0.9827 0.00041
SUM159PT Palbociclib
0.0031623
CDK4/6
Cell cycle
 0.9798 0.00006
SUM159PT Palbociclib
0.01
CDK4/6
Cell cycle
 0.9438 0.00075
SUM159PT Palbociclib
0.031623
CDK4/6
Cell cycle
 0.8740 -0.00356
SUM159PT Palbociclib
0.1
CDK4/6
Cell cycle
 0.7573 -0.00332
SUM159PT Palbociclib
0.31623
CDK4/6
Cell cycle
 0.6445 -0.00282
SUM159PT Palbociclib
1.0
CDK4/6
Cell cycle
 0.5333 -0.00180
SUM159PT Palbociclib
3.1623
CDK4/6
Cell cycle
 0.3876 0.00480
SUM159PT AZD7762
0.001
CHK1/2
Cell cycle
 1.0206 -0.00007
SUM159PT AZD7762
0.0031623
CHK1/2
Cell cycle
 1.0276 -0.00021
SUM159PT AZD7762
0.01
CHK1/2
Cell cycle
 1.0325 0.00052