Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1143 Dinaciclib
1.0
pan CDK
Cell cycle
 -0.2265 0.24114
HCC1143 Cisplatin
0.0010833
Chemo
Chemotherapy
 1.0678 -0.00197
HCC1143 Cisplatin
0.0033333
Chemo
Chemotherapy
 0.9090 0.00336
HCC1143 Cisplatin
0.01
Chemo
Chemotherapy
 0.8651 0.00104
HCC1143 Cisplatin
0.031667
Chemo
Chemotherapy
 0.9882 -0.00026
HCC1143 Cisplatin
0.1
Chemo
Chemotherapy
 0.9190 0.00951
HCC1143 Cisplatin
0.31623
Chemo
Chemotherapy
 0.7737 0.01236
HCC1143 Cisplatin
1.0
Chemo
Chemotherapy
 0.4865 0.09227
HCC1143 Cisplatin
3.1623
Chemo
Chemotherapy
 0.0754 0.14802
HCC1143 Cisplatin
10.0
Chemo
Chemotherapy
 0.0813 0.09827
HCC1143 Doxorubicin
0.00031623
Chemo
Chemotherapy
 0.9177 0.00141
HCC1143 Doxorubicin
0.001
Chemo
Chemotherapy
 0.9297 0.00305
HCC1143 Doxorubicin
0.0031623
Chemo
Chemotherapy
 0.8035 0.01115
HCC1143 Doxorubicin
0.01
Chemo
Chemotherapy
 0.5106 0.07501
HCC1143 Doxorubicin
0.031623
Chemo
Chemotherapy
 0.0290 0.16077
HCC1143 Doxorubicin
0.1
Chemo
Chemotherapy
 -0.0411 0.14868
HCC1143 Doxorubicin
0.31623
Chemo
Chemotherapy
 -0.1108 0.23055
HCC1143 Doxorubicin
1.0
Chemo
Chemotherapy
 -0.1981 0.34049
HCC1143 Doxorubicin
3.1623
Chemo
Chemotherapy
 -0.2511 0.29033
HCC1143 Taxol
0.0001
Chemo
Chemotherapy
 0.8765 0.01572
HCC1143 Taxol
0.00031623
Chemo
Chemotherapy
 1.0068 -0.00212
HCC1143 Taxol
0.001
Chemo
Chemotherapy
 0.8917 0.03177
HCC1143 Taxol
0.0031623
Chemo
Chemotherapy
 0.1532 0.29137
HCC1143 Taxol
0.01
Chemo
Chemotherapy
 -0.2338 0.45890
HCC1143 Taxol
0.031623
Chemo
Chemotherapy
 -0.2478 0.47575