Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAL-85-1 Trametinib
0.00031623
MEK
MAPK/nRTK
 1.0163 0.00507
CAL-85-1 Trametinib
0.001
MEK
MAPK/nRTK
 0.8963 0.02128
CAL-85-1 Trametinib
0.0031623
MEK
MAPK/nRTK
 0.7038 0.04994
CAL-85-1 Trametinib
0.01
MEK
MAPK/nRTK
 0.5912 0.10154
CAL-85-1 Trametinib
0.031623
MEK
MAPK/nRTK
 0.3708 0.16255
CAL-85-1 Trametinib
0.1
MEK
MAPK/nRTK
 0.2598 0.23316
CAL-85-1 Trametinib
0.31623
MEK
MAPK/nRTK
 0.2578 0.23687
CAL-85-1 Trametinib
1.0
MEK
MAPK/nRTK
 0.2343 0.24896
CAL-85-1 Saracatinib
0.001
SRC
MAPK/nRTK
 1.1030 -0.00387
CAL-85-1 Saracatinib
0.0031623
SRC
MAPK/nRTK
 1.0183 0.01325
CAL-85-1 Saracatinib
0.01
SRC
MAPK/nRTK
 1.1810 0.00294
CAL-85-1 Saracatinib
0.031623
SRC
MAPK/nRTK
 1.1310 0.00706
CAL-85-1 Saracatinib
0.1
SRC
MAPK/nRTK
 1.0775 0.02771
CAL-85-1 Saracatinib
0.31623
SRC
MAPK/nRTK
 0.8485 0.07899
CAL-85-1 Saracatinib
1.0
SRC
MAPK/nRTK
 0.4396 0.17248
CAL-85-1 Saracatinib
3.1623
SRC
MAPK/nRTK
 0.2237 0.25455
CAL-85-1 Saracatinib
10.0
SRC
MAPK/nRTK
 0.1156 0.29383
CAL-85-1 ABT-737
0.001
Bcl2/XL
Misc
 1.0471 -0.00849
CAL-85-1 ABT-737
0.0031623
Bcl2/XL
Misc
 1.0609 -0.01214
CAL-85-1 ABT-737
0.01
Bcl2/XL
Misc
 1.0797 -0.00817
CAL-85-1 ABT-737
0.031623
Bcl2/XL
Misc
 1.0962 -0.00375
CAL-85-1 ABT-737
0.1
Bcl2/XL
Misc
 1.0393 0.00420
CAL-85-1 ABT-737
0.31623
Bcl2/XL
Misc
 1.0819 -0.00800
CAL-85-1 ABT-737
1.0
Bcl2/XL
Misc
 1.1181 0.00911
CAL-85-1 ABT-737
3.1623
Bcl2/XL
Misc
 0.9343 0.03598