LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
---|---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Neratinib | 89.69 | 11.9 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | 0.5370 |
MCF 10A-H2B-mCherry | Alpelisib | 64.49 | 11.9 | Inf | Inf | 0.9987 | 0.9987 | 0.0000 | 0.0154 |
MCF 10A-H2B-mCherry | Alpelisib | 66.19 | 11.9 | Inf | Inf | 0.9907 | 0.9907 | 0.0000 | 0.0377 |
MCF 10A-H2B-mCherry | Alpelisib | 54.25 | 11.9 | Inf | Inf | 0.9331 | 0.9259 | 2.5000 | -0.0161 |
MCF 10A-H2B-mCherry | Alpelisib | 55.97 | 11.9 | Inf | Inf | 0.9301 | 0.9223 | 2.5000 | -0.0036 |
MCF 10A-H2B-mCherry | Alpelisib | 67.89 | 11.9 | Inf | Inf | 0.9130 | 0.9130 | 0.0000 | 0.0702 |
MCF 10A-H2B-mCherry | Alpelisib | 61.08 | 11.9 | Inf | Inf | 0.9110 | 0.9110 | 0.0000 | 0.0261 |
MCF 10A-H2B-mCherry | Alpelisib | 57.67 | 11.9 | Inf | Inf | 0.9066 | 0.8952 | 2.5000 | 0.0030 |
MCF 10A-H2B-mCherry | Alpelisib | 62.78 | 11.9 | Inf | Inf | 0.9043 | 0.9043 | 0.0000 | 0.0082 |
MCF 10A-H2B-mCherry | Alpelisib | 59.37 | 11.9 | Inf | Inf | 0.9024 | 0.9024 | 0.0000 | 0.0172 |
MCF 10A-H2B-mCherry | Alpelisib | 52.56 | 11.9 | Inf | Inf | 0.8858 | 0.8764 | 2.5000 | -0.0107 |
MCF 10A-H2B-mCherry | Alpelisib | 50.86 | 11.9 | Inf | Inf | 0.8643 | 0.8641 | 2.5000 | 0.0066 |
MCF 10A-H2B-mCherry | Alpelisib | 69.60 | 11.9 | Inf | Inf | 0.8288 | 0.8288 | 0.0000 | 0.0594 |
MCF 10A-H2B-mCherry | Alpelisib | 49.15 | 11.9 | Inf | Inf | 0.8148 | 0.8290 | 2.4998 | 0.0068 |
MCF 10A-H2B-mCherry | Alpelisib | 45.74 | 11.9 | Inf | Inf | 0.8089 | 0.1521 | 0.3040 | 0.0556 |
MCF 10A-H2B-mCherry | Alpelisib | 71.30 | 11.9 | Inf | Inf | 0.8057 | 0.8057 | 0.0000 | 0.0922 |
MCF 10A-H2B-mCherry | Alpelisib | 44.03 | 11.9 | Inf | Inf | 0.8013 | -0.0883 | 0.3719 | 0.0392 |
MCF 10A-H2B-mCherry | Alpelisib | 47.45 | 11.9 | Inf | Inf | 0.7990 | 0.8167 | 0.9724 | 0.0230 |
MCF 10A-H2B-mCherry | Alpelisib | 42.33 | 11.9 | Inf | 10.3523 | 0.7387 | 0.3591 | 3.2502 | 0.0201 |
MCF 10A-H2B-mCherry | Alpelisib | 40.63 | 11.9 | Inf | 7.2456 | 0.7345 | 0.6596 | 5.0000 | 0.0088 |
MCF 10A-H2B-mCherry | Alpelisib | 38.93 | 11.9 | Inf | 6.4483 | 0.6837 | 0.6427 | 5.0000 | 0.0115 |
MCF 10A-H2B-mCherry | Alpelisib | 37.23 | 11.9 | Inf | 26.561 | 0.6750 | -0.1747 | 3.0317 | 0.0360 |
MCF 10A-H2B-mCherry | Alpelisib | 32.11 | 11.9 | Inf | 17.6088 | 0.6518 | -0.2106 | 0.9909 | 0.0628 |
MCF 10A-H2B-mCherry | Alpelisib | 28.71 | 11.9 | Inf | 14.3094 | 0.6464 | -0.1118 | 1.3594 | 0.0750 |
MCF 10A-H2B-mCherry | Taxol | 69.60 | 11.9 | Inf | Inf | 0.6450 | 0.3071 | 2.4999 | 0.7524 |