LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)

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Cell Small Molecule Time Point (hr) Time Interval (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Dasatinib 54.25 11.9
2.4281
8.3283
-0.3369 -1.0000 1.0304 0.2327
MCF 10A-H2B-mCherry Dasatinib 55.97 11.9
4.1363
6.7932
-0.4294 -1.0000 3.3320 0.2248
MCF 10A-H2B-mCherry Neratinib 57.67 11.9
0.4637
1.3072
-0.6943 -1.0000 1.2533 0.2654
MCF 10A-H2B-mCherry Palbociclib 73.49 11.9
3.8592
5.0055
-0.9830 -1.0000 4.3323 0.1600
MCF 10A-H2B-mCherry Neratinib 55.97 11.9
0.4248
1.1732
-0.6983 -1.0000 1.2159 0.2772
MCF 10A-H2B-mCherry Etoposide 18.49 11.9
1.6291
11.8949
0.0238 -1.0000 0.5835 0.2602
MCF 10A-H2B-mCherry Palbociclib 80.31 11.9
3.7073
4.6207
-0.9998 -1.0000 5.0000 0.2973
MCF 10A-H2B-mCherry Neratinib 80.31 11.9
Inf
Inf
-1.0000 -1.0000 0.0000 0.3828
MCF 10A-H2B-mCherry Neratinib 73.49 11.9
Inf
Inf
-1.0000 -1.0000 0.0000 0.4286
MCF 10A-H2B-mCherry Palbociclib 76.90 11.9
3.8753
4.8812
-0.9978 -1.0000 4.7782 0.1974
MCF 10A-H2B-mCherry Dasatinib 49.15 11.9
0.8818
11.0074
-0.2493 -1.0000 0.4675 0.3252
MCF 10A-H2B-mCherry Neratinib 76.90 11.9
Inf
Inf
-1.0000 -1.0000 0.0000 0.3500
MCF 10A-H2B-mCherry Dasatinib 52.56 11.9
1.4789
9.4423
-0.2797 -1.0000 0.6283 0.2800
MCF 10A-H2B-mCherry Dasatinib 50.86 11.9
1.1058
12.4343
-0.2680 -1.0000 0.4767 0.3013
MCF 10A-H2B-mCherry Etoposide 16.79 11.9
2.2187
15.6011
0.0196 -1.0000 0.6178 0.2349
MCF 10A-H2B-mCherry Alpelisib 89.69 11.9
Inf
Inf
-0.9954 -0.9954 0.0000 1.0518
MCF 10A-H2B-mCherry Palbociclib 85.43 11.9
Inf
Inf
-0.9917 -0.9933 0.6160 0.5482
MCF 10A-H2B-mCherry Palbociclib 85.43 12.0
Inf
Inf
-0.9908 -0.9912 0.5687 0.5120
MCF 10A-H2B-mCherry Alpelisib 85.43 11.9
Inf
Inf
-0.9874 -0.9874 0.0000 0.8979
MCF 10A-H2B-mCherry Alpelisib 85.43 12.0
Inf
Inf
-0.9870 -0.9870 0.0000 0.8881
MCF 10A-H2B-mCherry Palbociclib 89.69 11.9
Inf
Inf
-0.9796 -0.9796 0.0000 0.6834
MCF 10A-H2B-mCherry Neratinib 54.25 11.9
0.45
1.3349
-0.6369 -0.9728 1.2215 0.2717
MCF 10A-H2B-mCherry Etoposide 80.31 11.9
Inf
Inf
-0.9514 -0.9514 0.0000 1.1514
MCF 10A-H2B-mCherry Alpelisib 80.31 11.9
Inf
Inf
-0.9481 -0.9481 0.0000 0.4247
MCF 10A-H2B-mCherry Dasatinib 89.69 11.9
Inf
Inf
-0.9466 -0.9466 0.0000 1.1164
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