LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 73.49 | 11.9 | Inf | Inf | -1.0000 | -1.0000 | 0.0000 | 0.4286 |
| MCF 10A-H2B-mCherry | Neratinib | 80.31 | 11.9 | Inf | Inf | -1.0000 | -1.0000 | 0.0000 | 0.3828 |
| MCF 10A-H2B-mCherry | Taxol | 80.31 | 11.9 | 0.0 | 0.0002 | -1.0000 | -0.8852 | 0.6794 | 1.4491 |
| MCF 10A-H2B-mCherry | Neratinib | 76.90 | 11.9 | Inf | Inf | -1.0000 | -1.0000 | 0.0000 | 0.3500 |
| MCF 10A-H2B-mCherry | Palbociclib | 80.31 | 11.9 | 3.7073 | 4.6207 | -0.9998 | -1.0000 | 5.0000 | 0.2973 |
| MCF 10A-H2B-mCherry | Palbociclib | 76.90 | 11.9 | 3.8753 | 4.8812 | -0.9978 | -1.0000 | 4.7782 | 0.1974 |
| MCF 10A-H2B-mCherry | Alpelisib | 89.69 | 11.9 | Inf | Inf | -0.9954 | -0.9954 | 0.0000 | 1.0518 |
| MCF 10A-H2B-mCherry | Palbociclib | 85.43 | 11.9 | Inf | Inf | -0.9917 | -0.9933 | 0.6160 | 0.5482 |
| MCF 10A-H2B-mCherry | Taxol | 85.43 | 11.9 | Inf | Inf | -0.9909 | -0.8242 | 2.4551 | 1.5351 |
| MCF 10A-H2B-mCherry | Palbociclib | 85.43 | 12.0 | Inf | Inf | -0.9908 | -0.9912 | 0.5687 | 0.5120 |
| MCF 10A-H2B-mCherry | Alpelisib | 85.43 | 11.9 | Inf | Inf | -0.9874 | -0.9874 | 0.0000 | 0.8979 |
| MCF 10A-H2B-mCherry | Alpelisib | 85.43 | 12.0 | Inf | Inf | -0.9870 | -0.9870 | 0.0000 | 0.8881 |
| MCF 10A-H2B-mCherry | Palbociclib | 73.49 | 11.9 | 3.8592 | 5.0055 | -0.9830 | -1.0000 | 4.3323 | 0.1600 |
| MCF 10A-H2B-mCherry | Palbociclib | 89.69 | 11.9 | Inf | Inf | -0.9796 | -0.9796 | 0.0000 | 0.6834 |
| MCF 10A-H2B-mCherry | Taxol | 76.90 | 11.9 | 0.0001 | 0.0003 | -0.9743 | -0.6652 | 0.7092 | 1.2470 |
| MCF 10A-H2B-mCherry | Taxol | 85.43 | 12.0 | Inf | Inf | -0.9704 | -0.7957 | 2.4990 | 1.5206 |
| MCF 10A-H2B-mCherry | Etoposide | 80.31 | 11.9 | Inf | Inf | -0.9514 | -0.9514 | 0.0000 | 1.1514 |
| MCF 10A-H2B-mCherry | Alpelisib | 80.31 | 11.9 | Inf | Inf | -0.9481 | -0.9481 | 0.0000 | 0.4247 |
| MCF 10A-H2B-mCherry | Dasatinib | 89.69 | 11.9 | Inf | Inf | -0.9466 | -0.9466 | 0.0000 | 1.1164 |
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 11.9 | Inf | Inf | -0.9117 | -0.9117 | 0.0000 | 0.9543 |
| MCF 10A-H2B-mCherry | Etoposide | 76.90 | 11.9 | Inf | Inf | -0.8928 | -0.8928 | 0.0000 | 1.0768 |
| MCF 10A-H2B-mCherry | Etoposide | 85.43 | 11.9 | Inf | Inf | -0.8878 | -0.8878 | 0.0000 | 1.1597 |
| MCF 10A-H2B-mCherry | Etoposide | 85.43 | 12.0 | Inf | Inf | -0.8811 | -0.8811 | 0.0000 | 1.1884 |
| MCF 10A-H2B-mCherry | Neratinib | 85.43 | 12.0 | Inf | Inf | -0.8789 | -0.8789 | 0.0000 | 0.5982 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.31 | 11.9 | Inf | Inf | -0.8783 | -0.8783 | 0.0000 | 0.8067 |