LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 71.30 | 11.9 | Inf | Inf | 0.8057 | 0.8057 | 0.0000 | 0.0922 |
| MCF 10A-H2B-mCherry | Alpelisib | 69.60 | 11.9 | Inf | Inf | 0.8288 | 0.8288 | 0.0000 | 0.0594 |
| MCF 10A-H2B-mCherry | Alpelisib | 66.19 | 11.9 | Inf | Inf | 0.9907 | 0.9907 | 0.0000 | 0.0377 |
| MCF 10A-H2B-mCherry | Alpelisib | 61.08 | 11.9 | Inf | Inf | 0.9110 | 0.9110 | 0.0000 | 0.0261 |
| MCF 10A-H2B-mCherry | Alpelisib | 64.49 | 11.9 | Inf | Inf | 0.9987 | 0.9987 | 0.0000 | 0.0154 |
| MCF 10A-H2B-mCherry | Alpelisib | 67.89 | 11.9 | Inf | Inf | 0.9130 | 0.9130 | 0.0000 | 0.0702 |
| MCF 10A-H2B-mCherry | Alpelisib | 57.67 | 11.9 | Inf | Inf | 0.9066 | 0.8952 | 2.5000 | 0.0030 |
| MCF 10A-H2B-mCherry | Alpelisib | 20.19 | 11.9 | Inf | Inf | 0.4666 | 0.4567 | 2.5000 | 0.1534 |
| MCF 10A-H2B-mCherry | Alpelisib | 21.90 | 11.9 | Inf | Inf | 0.4426 | 0.4238 | 2.5000 | 0.1686 |
| MCF 10A-H2B-mCherry | Alpelisib | 59.37 | 11.9 | Inf | Inf | 0.9024 | 0.9024 | 0.0000 | 0.0172 |
| MCF 10A-H2B-mCherry | Alpelisib | 23.60 | 11.9 | Inf | Inf | 0.5168 | 0.4975 | 2.5000 | 0.1285 |
| MCF 10A-H2B-mCherry | Alpelisib | 15.08 | 11.9 | Inf | Inf | 0.4895 | 0.4895 | 0.0000 | 0.1563 |
| MCF 10A-H2B-mCherry | Alpelisib | 18.49 | 11.9 | Inf | Inf | 0.4464 | 0.5217 | 2.5000 | 0.1547 |
| MCF 10A-H2B-mCherry | Alpelisib | 62.78 | 11.9 | Inf | Inf | 0.9043 | 0.9043 | 0.0000 | 0.0082 |
| MCF 10A-H2B-mCherry | Alpelisib | 27.00 | 11.9 | Inf | Inf | 0.6407 | 0.6557 | 0.5188 | 0.0807 |
| MCF 10A-H2B-mCherry | Alpelisib | 16.79 | 11.9 | Inf | Inf | 0.4687 | 0.5844 | 2.5000 | 0.1607 |
| MCF 10A-H2B-mCherry | Alpelisib | 44.03 | 11.9 | Inf | Inf | 0.8013 | -0.0883 | 0.3719 | 0.0392 |
| MCF 10A-H2B-mCherry | Alpelisib | 45.74 | 11.9 | Inf | Inf | 0.8089 | 0.1521 | 0.3040 | 0.0556 |
| MCF 10A-H2B-mCherry | Alpelisib | 47.45 | 11.9 | Inf | Inf | 0.7990 | 0.8167 | 0.9724 | 0.0230 |
| MCF 10A-H2B-mCherry | Alpelisib | 49.15 | 11.9 | Inf | Inf | 0.8148 | 0.8290 | 2.4998 | 0.0068 |
| MCF 10A-H2B-mCherry | Alpelisib | 50.86 | 11.9 | Inf | Inf | 0.8643 | 0.8641 | 2.5000 | 0.0066 |
| MCF 10A-H2B-mCherry | Alpelisib | 52.56 | 11.9 | Inf | Inf | 0.8858 | 0.8764 | 2.5000 | -0.0107 |
| MCF 10A-H2B-mCherry | Alpelisib | 54.25 | 11.9 | Inf | Inf | 0.9331 | 0.9259 | 2.5000 | -0.0161 |
| MCF 10A-H2B-mCherry | Alpelisib | 55.97 | 11.9 | Inf | Inf | 0.9301 | 0.9223 | 2.5000 | -0.0036 |
| MCF 10A-H2B-mCherry | Alpelisib | 73.49 | 11.9 | Inf | Inf | -0.1025 | -0.1025 | 0.0000 | 0.1541 |