Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
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A-375 | Vemurafenib | Saracatinib | 0.316 | 3.160 | uM | 72 | hr | 3 | 1316 | 53 | 0.0661 | 0.0757 | 0.0403 | 0.0403 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 0.000 | uM | 72 | hr | 1 | 3640 | 140 | 0.1832 | 0.1915 | 0.0385 | 0.0418 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 0.000 | uM | 72 | hr | 2 | 3900 | 189 | 0.1943 | 0.1915 | 0.0485 | 0.0418 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 0.000 | uM | 72 | hr | 3 | 3917 | 151 | 0.1971 | 0.1915 | 0.0385 | 0.0418 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 0.316 | uM | 72 | hr | 1 | 2328 | 167 | 0.1131 | 0.1190 | 0.0717 | 0.0733 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 0.316 | uM | 72 | hr | 2 | 2557 | 190 | 0.1239 | 0.1190 | 0.0743 | 0.0733 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 0.316 | uM | 72 | hr | 3 | 2475 | 183 | 0.1200 | 0.1190 | 0.0739 | 0.0733 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 1.000 | uM | 72 | hr | 1 | 1638 | 157 | 0.0775 | 0.0717 | 0.0958 | 0.0989 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 1.000 | uM | 72 | hr | 2 | 1536 | 170 | 0.0715 | 0.0717 | 0.1107 | 0.0989 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 1.000 | uM | 72 | hr | 3 | 1386 | 125 | 0.0660 | 0.0717 | 0.0902 | 0.0989 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 3.160 | uM | 72 | hr | 1 | 1317 | 141 | 0.0616 | 0.0571 | 0.1071 | 0.0996 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 3.160 | uM | 72 | hr | 2 | 1204 | 111 | 0.0572 | 0.0571 | 0.0922 | 0.0996 |
A-375 | Vemurafenib | Saracatinib | 1.000 | 3.160 | uM | 72 | hr | 3 | 1115 | 111 | 0.0526 | 0.0571 | 0.0996 | 0.0996 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 0.000 | uM | 72 | hr | 1 | 3381 | 232 | 0.1648 | 0.1538 | 0.0686 | 0.0753 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 0.000 | uM | 72 | hr | 2 | 3197 | 255 | 0.1540 | 0.1538 | 0.0798 | 0.0753 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 0.000 | uM | 72 | hr | 3 | 2950 | 229 | 0.1424 | 0.1538 | 0.0776 | 0.0753 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 0.316 | uM | 72 | hr | 1 | 2098 | 334 | 0.0923 | 0.0842 | 0.1592 | 0.1524 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 0.316 | uM | 72 | hr | 2 | 1856 | 299 | 0.0815 | 0.0842 | 0.1611 | 0.1524 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 0.316 | uM | 72 | hr | 3 | 1744 | 239 | 0.0788 | 0.0842 | 0.1370 | 0.1524 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 1.000 | uM | 72 | hr | 1 | 1524 | 308 | 0.0637 | 0.0584 | 0.2021 | 0.2015 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 1.000 | uM | 72 | hr | 2 | 1511 | 288 | 0.0640 | 0.0584 | 0.1906 | 0.2015 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 1.000 | uM | 72 | hr | 3 | 1152 | 244 | 0.0475 | 0.0584 | 0.2118 | 0.2015 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 3.160 | uM | 72 | hr | 1 | 1136 | 225 | 0.0477 | 0.0453 | 0.1981 | 0.2134 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 3.160 | uM | 72 | hr | 2 | 1114 | 238 | 0.0459 | 0.0453 | 0.2136 | 0.2134 |
A-375 | Vemurafenib | Saracatinib | 3.160 | 3.160 | uM | 72 | hr | 3 | 1046 | 239 | 0.0422 | 0.0453 | 0.2285 | 0.2134 |