Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset (ID:20269)

Download: Excel (XLSX), Comma-separated (CSV)

<<<<

Select the entities to show:

Small molecules	Cells	Antibodies

|<
<<
Previous
Page 12 of 370
Next
>>
>
276 to 300 of 9248 records
per page:

Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Biological Replicate ID	Conc Unit	GR50	GEC50	GRmax	GRinf	GR Hill Coefficient	GR_AOC	GR r2	Nominal Division Rate
184B5	NM	Basal	Oxamflatin	HDAC	HDAC	12566.147	uM	1.13190	3.48360	-0.8575	-1.0000	0.9773	0.5020	0.9814	1.6169
184A1	NM	Basal	Sirolimus	MTOR	MTOR	7787.068	uM	inf	inf	-0.2794	-0.2794	0.0000	0.5821	0.4995	0.9562
184A1	NM	Basal	GSK1838705A	IGF1R	RTK	5895.098	uM	0.42849	0.39937	0.0166	0.0538	1.6165	0.3574	0.9937	1.4041
184A1	NM	Basal	Dactolisib	PI3K	PI3K	12509.155	uM	0.06399	0.05482	0.0859	0.0731	1.0226	0.4688	0.9812	1.3444
184A1	NM	Basal	Bortezomib	Proteasome	Proteasome	5894.074	uM	0.03715	0.13270	-0.6899	-0.6765	0.6722	0.9059	0.9559	1.4541
184B5	NM	Basal	Oxaliplatin	DNA cross-linker	DNA cross-linker	9095.119	uM	3.22860	15.96270	-0.9485	-1.0000	0.6874	0.6144	0.9570	1.2263
184B5	NM	Basal	Omipalisib	PI3K	PI3K	5897.086	uM	0.00620	0.01729	-0.6593	-0.4574	0.6340	0.8271	0.9483	1.2814
184A1	NM	Basal	Sigma A6730	AKT	AKT	12509.165	uM	3.14240	13.05610	-0.6553	-1.0000	0.7714	0.3161	0.9885	1.5022
184B5	NM	Basal	Olomoucine II	CDK1	CDK	12566.147	uM	3.35670	5.86570	-0.3694	-0.4572	1.1635	0.3493	0.9899	1.6169
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	5897.066	uM	13.78730	20.17590	-0.9537	-1.0000	2.8854	0.1920	0.9917	1.2737
184A1	NM	Basal	Selumetinib	MEK	MAPK	12509.155	uM	0.33719	0.32458	0.0422	0.0182	0.9722	0.3745	0.9924	1.3444
184A1	NM	Basal	GSK1838705A	IGF1R	RTK	5895.091	uM	0.38664	0.64104	-0.6029	-0.4621	1.2945	0.5672	0.9684	1.1729
184B5	NM	Basal	Nutlin 3a	MDM2	MDM2	5896.066	uM	2.29050	11.45910	-0.9381	-1.0000	0.6824	0.3705	0.8514	1.4224
184B5	NM	Basal	NU6102	CDK1/2	CDK	12566.147	uM	4.55970	10.7450	-0.8630	-1.0000	1.2816	0.2945	0.9979	1.6169
184A1	NM	Basal	SB-3CT	MMP2/9	MMP	12509.168	uM	433.25760	1000.00000	0.6180	-0.2672	0.5118	0.0585	0.8869	1.3516
184B5	NM	Basal	NSC 663284	CDC25	CDC	12566.152	uM	2.37290	3.20490	-0.8860	-0.8796	3.3767	0.5784	0.9988	1.4827
184B5	NM	Basal	Nilotinib	ABL	nRTK	12566.17	uM	inf	0.08710	0.9223	0.9254	0.8046	0.0464	0.8541	1.4648
184A1	NM	Basal	QNZ	NFkB	NFKB	5895.096	uM	97.09330	12.46050	0.5808	0.2658	0.3693	0.1340	0.8974	1.4232
184A1	NM	Basal	GSK1070916	AURK	AURK	10002.001	uM	0.64737	2.67080	-0.5505	-0.8031	0.6759	0.3916	0.9922	0.5372
184A1	NM	Basal	CPT-11	TOP1	TOP	10002.034	uM	3.43020	4.22870	-0.9255	-0.9233	4.9992	0.4247	0.9962	0.6736
184B5	NM	Basal	Nelfinavir			12979.174	uM	5.2970	7.9410	-0.7445	-0.8032	2.3659	0.1847	0.9934	1.5680
184B5	NM	Basal	Pevonedistat	NAE1	NAE1	12566.135	uM	0.15715	0.62079	-0.4838	-0.5023	0.5062	0.5445	0.9747	1.6384
184A1	NM	Basal	Purvalanol A	CDK1	CDK	5894.067	uM	6.00880	4.73440	0.1064	0.1488	1.4817	0.2344	0.9798	1.5647
184B5	NM	Basal	MG-132	Proteasome	Proteasome	12566.17	uM	0.01702	0.03186	-0.6444	-0.5157	1.1297	0.9111	0.9667	1.4648
184B5	NM	Basal	MG-132	Proteasome	Proteasome	12566.17	uM	0.01702	0.03186	-0.6444	-0.5157	1.1297	0.9111	0.9667	1.4648

|<
<<
Previous
Page 12 of 370
Next
>>
>
276 to 300 of 9248 records
per page:

HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset (ID:20269)