Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7450.074 | 1.0142 | 1.0127 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7450.074 | 0.9901 | 0.9911 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7450.074 | 1.0387 | 1.0343 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7450.074 | 1.0100 | 1.0089 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7450.074 | 1.1732 | 1.1483 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7450.074 | 0.5317 | 0.5073 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7450.074 | 0.3256 | 0.2102 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7450.074 | 0.1057 | -0.2686 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7450.074 | 0.0739 | -0.3770 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7451.074 | 0.9479 | 0.9515 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7451.074 | 0.9387 | 0.9428 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7451.074 | 0.9542 | 0.9575 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7451.074 | 0.9329 | 0.9373 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7451.074 | 0.8722 | 0.8784 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7451.074 | 0.5718 | 0.5477 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7451.074 | 0.2461 | 0.0513 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7451.074 | 0.0930 | -0.3272 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7451.074 | 0.0843 | -0.3569 | 2.1799 | |
| HCC1937 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7452.074 | 1.0673 | 1.0878 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7452.074 | 1.0764 | 1.0995 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7452.074 | 1.0178 | 1.0234 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7452.074 | 1.0595 | 1.0778 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7452.074 | 0.9809 | 0.9747 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7452.074 | 0.7135 | 0.6009 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7452.074 | 0.4412 | 0.1659 | 1.5162 |