Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 5899.074 | 0.9108 | 0.7997 | 0.8860 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 5899.074 | 0.9396 | 0.8643 | 0.8860 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 5899.074 | 0.8271 | 0.6143 | 0.8860 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 5899.074 | 0.7663 | 0.4811 | 0.8860 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 5899.074 | 0.4515 | -0.1848 | 0.8860 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 5899.074 | 0.4800 | -0.1265 | 0.8860 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 5899.074 | 0.4064 | -0.2761 | 0.8860 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 5900.074 | 1.0013 | 1.0011 | 2.4189 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 5900.074 | 1.0233 | 1.0192 | 2.4189 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 5900.074 | 1.0437 | 1.0356 | 2.4189 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 5900.074 | 1.0139 | 1.0114 | 2.4189 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 5900.074 | 0.7385 | 0.7644 | 2.4189 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 5900.074 | 0.1619 | -0.0578 | 2.4189 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 5900.074 | 0.0698 | -0.3346 | 2.4189 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 5900.074 | 0.0362 | -0.4929 | 2.4189 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 5900.074 | 0.0259 | -0.5584 | 2.4189 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 5901.074 | 0.9641 | 0.9614 | 1.8718 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 5901.074 | 0.9929 | 0.9924 | 1.8718 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 5901.074 | 0.9465 | 0.9421 | 1.8718 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 5901.074 | 0.9669 | 0.9644 | 1.8718 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 5901.074 | 0.5572 | 0.4633 | 1.8718 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 5901.074 | 0.1575 | -0.2549 | 1.8718 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 5901.074 | 0.0738 | -0.5031 | 1.8718 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 5901.074 | 0.0380 | -0.6514 | 1.8718 | |
| AU565 | HER2amp | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 5901.074 | 0.0270 | -0.7095 | 1.8718 |