Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 0.533 | uM | 5896.074 | 0.7564 | 0.6413 | 1.4124 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 2.67 | uM | 5896.074 | 0.7561 | 0.6408 | 1.4124 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 13.3 | uM | 5896.074 | 0.6113 | 0.4116 | 1.4124 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 66.7 | uM | 5896.074 | 0.3134 | -0.1204 | 1.4124 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 333 | uM | 5896.074 | 0.1609 | -0.4513 | 1.4124 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 0.000853 | uM | 5897.074 | 0.9709 | 0.9545 | 1.2824 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 0.00427 | uM | 5897.074 | 0.9524 | 0.9254 | 1.2824 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 0.0213 | uM | 5897.074 | 0.9556 | 0.9305 | 1.2824 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 0.107 | uM | 5897.074 | 0.9431 | 0.9107 | 1.2824 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 0.533 | uM | 5897.074 | 0.9350 | 0.8979 | 1.2824 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 2.67 | uM | 5897.074 | 0.9100 | 0.8583 | 1.2824 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 13.3 | uM | 5897.074 | 0.7792 | 0.6464 | 1.2824 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 66.7 | uM | 5897.074 | 0.4955 | 0.1567 | 1.2824 | |
| 184B5 | NM | Basal | Etoposide | TOP2 | TOP | 333 | uM | 5897.074 | 0.3504 | -0.1173 | 1.2824 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 5898.074 | 1.0077 | 1.0216 | 0.7134 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 5898.074 | 0.9799 | 0.9437 | 0.7134 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 5898.074 | 0.9875 | 0.9650 | 0.7134 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 5898.074 | 0.9463 | 0.8511 | 0.7134 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 5898.074 | 0.9834 | 0.9535 | 0.7134 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 5898.074 | 0.9528 | 0.8690 | 0.7134 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 5898.074 | 0.8455 | 0.5806 | 0.7134 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 5898.074 | 0.5859 | -0.0547 | 0.7134 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 5898.074 | 0.5232 | -0.1933 | 0.7134 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 5899.074 | 0.9816 | 0.9586 | 0.8860 | |
| 600MPE | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 5899.074 | 0.9822 | 0.9599 | 0.8860 |