Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7540.05 | 0.1786 | -0.8392 | 0.6835 | |
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7540.05 | 0.2388 | -0.7540 | 0.6835 | |
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9878.037 | 1.0182 | 1.0304 | 1.1983 | |
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9878.037 | 1.1198 | 1.1981 | 1.1983 | |
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9878.037 | 0.9802 | 0.9668 | 1.1983 | |
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9878.037 | 0.6923 | 0.4715 | 1.1983 | |
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9878.037 | 0.3752 | -0.1175 | 1.1983 | |
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9878.037 | 0.3232 | -0.2207 | 1.1983 | |
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9878.037 | 0.3065 | -0.2545 | 1.1983 | |
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9878.037 | 0.1043 | -0.6967 | 1.1983 | |
| SUM52PE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9878.037 | 0.0468 | -0.8447 | 1.1983 | |
| T47D | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9033.05 | 0.9830 | 0.9740 | 1.3061 | |
| T47D | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9033.05 | 0.9950 | 0.9924 | 1.3061 | |
| T47D | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9033.05 | 0.9646 | 0.9455 | 1.3061 | |
| T47D | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9033.05 | 1.0151 | 1.0230 | 1.3061 | |
| T47D | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9033.05 | 0.9418 | 0.9103 | 1.3061 | |
| T47D | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9033.05 | 0.7530 | 0.6096 | 1.3061 | |
| T47D | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9033.05 | 0.4349 | 0.0571 | 1.3061 | |
| T47D | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9033.05 | 0.3637 | -0.0781 | 1.3061 | |
| T47D | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9033.05 | 0.3541 | -0.0968 | 1.3061 | |
| UACC-893 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9045.05 | 0.9598 | 0.8990 | 0.7910 | |
| UACC-893 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9045.05 | 1.1532 | 1.3948 | 0.7910 | |
| UACC-893 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9045.05 | 0.9270 | 0.8172 | 0.7910 | |
| UACC-893 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9045.05 | 0.8904 | 0.7271 | 0.7910 | |
| UACC-893 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9045.05 | 0.2384 | -0.6735 | 0.7910 |