Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7900.037 | 1.0481 | 1.1454 | 0.6692 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7900.037 | 0.7335 | 0.2586 | 0.6692 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7900.037 | 0.4823 | -0.3273 | 0.6692 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7900.037 | 1.2311 | 1.7288 | 0.6692 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7900.037 | 0.7922 | 0.4120 | 0.6692 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7900.037 | 0.7229 | 0.2316 | 0.6692 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7900.037 | 0.7490 | 0.2985 | 0.6692 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7900.037 | 0.2626 | -0.7288 | 0.6692 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7900.037 | 0.1819 | -0.8433 | 0.6692 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7902.05 | 0.9532 | 0.9479 | 1.8149 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7902.05 | 1.2464 | 1.2580 | 1.8149 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7902.05 | 0.8398 | 0.8165 | 1.8149 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7902.05 | 1.0372 | 1.0407 | 1.8149 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7902.05 | 0.7019 | 0.6456 | 1.8149 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7902.05 | 0.5937 | 0.5006 | 1.8149 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7902.05 | 0.5204 | 0.3955 | 1.8149 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7902.05 | 0.4512 | 0.2901 | 1.8149 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7902.05 | 0.1602 | -0.2709 | 1.8149 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 10266.037 | 1.0010 | 1.0025 | 0.7695 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 10266.037 | 1.2043 | 1.5465 | 0.7695 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 10266.037 | 0.9782 | 0.9435 | 0.7695 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 10266.037 | 1.0274 | 1.0714 | 0.7695 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 10266.037 | 0.7861 | 0.4629 | 0.7695 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 10266.037 | 0.6462 | 0.1339 | 0.7695 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 10266.037 | 0.5742 | -0.0275 | 0.7695 |