Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7896.017 | 0.9879 | 0.9762 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7896.017 | 0.6709 | 0.3477 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7896.017 | 0.0552 | -0.8860 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7896.017 | 0.2897 | -0.4126 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7896.017 | 0.2023 | -0.5881 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7896.017 | 0.0002 | -0.9995 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9648.017 | 1.0181 | 1.0638 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9648.017 | 1.0452 | 1.1605 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 9648.017 | 1.0440 | 1.1561 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9648.017 | 1.0385 | 1.1364 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 9648.017 | 0.4899 | -0.4247 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 9648.017 | 0.1650 | -0.9139 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 9648.017 | 0.4065 | -0.5846 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 9648.017 | 0.0764 | -0.9776 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 9648.017 | 0.0016 | -1.0000 | 0.5727 | |
| MDA-MB-415 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7897.035 | 0.9660 | 0.9190 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7897.035 | 0.9805 | 0.9535 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7897.035 | 0.9548 | 0.8925 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7897.035 | 0.9927 | 0.9827 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7897.035 | 0.8601 | 0.6707 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7897.035 | 0.3762 | -0.3772 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7897.035 | 0.3142 | -0.4977 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7897.035 | 0.0765 | -0.9070 | 0.8378 | |
| MDA-MB-415 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7897.035 | 0.0005 | -0.9998 | 0.8378 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7898.017 | 1.0739 | 1.1272 | 1.1556 |