Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7898.017 | 0.8190 | 0.6827 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7898.017 | 1.0481 | 1.0830 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7898.017 | 0.8741 | 0.7801 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7898.017 | 0.7209 | 0.5068 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7898.017 | 0.4327 | -0.0313 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7898.017 | 0.3896 | -0.1153 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7898.017 | 0.3899 | -0.1148 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7898.017 | 0.0509 | -0.8480 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7899.017 | 0.9524 | 0.9527 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7899.017 | 0.8628 | 0.8604 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7899.017 | 1.1402 | 1.1329 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7899.017 | 0.8696 | 0.8675 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7899.017 | 0.8451 | 0.8416 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7899.017 | 0.5686 | 0.5164 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7899.017 | 0.4146 | 0.2988 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7899.017 | 0.4525 | 0.3558 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7899.017 | 0.2095 | -0.0707 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7900.017 | 1.1001 | 1.3879 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7900.017 | 1.0348 | 1.1312 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7900.017 | 0.9757 | 0.9108 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7900.017 | 1.1997 | 1.8049 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7900.017 | 1.2124 | 1.8602 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7900.017 | 0.6532 | -0.0932 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7900.017 | 0.5842 | -0.2632 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7900.017 | 0.6250 | -0.1646 | 0.5383 |