Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7921.04 | 0.9754 | 0.9367 | 0.7738 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7921.04 | 0.8501 | 0.6214 | 0.7738 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7921.04 | 0.2613 | -0.6470 | 0.7738 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7921.04 | 0.2997 | -0.5785 | 0.7738 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7921.04 | 0.2611 | -0.6474 | 0.7738 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7921.04 | 0.1970 | -0.7549 | 0.7738 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7921.04 | 0.0425 | -0.9663 | 0.7738 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 10146.037 | 1.1263 | 1.3609 | 0.7169 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 10146.037 | 1.1069 | 1.3044 | 0.7169 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 10146.037 | 1.1523 | 1.4373 | 0.7169 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 10146.037 | 0.5538 | -0.1229 | 0.7169 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 10146.037 | 0.1793 | -0.8181 | 0.7169 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 10146.037 | 0.1843 | -0.8110 | 0.7169 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 10146.037 | 0.1330 | -0.8801 | 0.7169 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 10146.037 | 0.4445 | -0.3545 | 0.7169 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 10146.037 | 0.0182 | -0.9925 | 0.7169 | |
| SUM229PE | TNBC | - | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7536.05 | 0.8925 | 0.7743 | 0.9494 | |
| SUM229PE | TNBC | - | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7536.05 | 1.1173 | 1.2478 | 0.9494 | |
| SUM229PE | TNBC | - | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7536.05 | 0.8289 | 0.6413 | 0.9494 | |
| SUM229PE | TNBC | - | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7536.05 | 0.8348 | 0.6535 | 0.9494 | |
| SUM229PE | TNBC | - | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7536.05 | 0.3820 | -0.2743 | 0.9494 | |
| SUM229PE | TNBC | - | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7536.05 | 0.2738 | -0.4890 | 0.9494 | |
| SUM229PE | TNBC | - | 17-AAG | HSP90 | HSP90 | 4 | uM | 7536.05 | 0.2892 | -0.4586 | 0.9494 | |
| SUM229PE | TNBC | - | 17-AAG | HSP90 | HSP90 | 20 | uM | 7536.05 | 0.1925 | -0.6473 | 0.9494 | |
| SUM229PE | TNBC | - | 17-AAG | HSP90 | HSP90 | 100 | uM | 7536.05 | 0.1960 | -0.6406 | 0.9494 |