Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7896.04 | 0.2989 | -0.3479 | 1.0776 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7896.04 | 0.1761 | -0.6008 | 1.0776 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7896.04 | 0.1729 | -0.6076 | 1.0776 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7896.04 | 0.1647 | -0.6250 | 1.0776 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7896.04 | 0.1461 | -0.6645 | 1.0776 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7896.05 | 1.0194 | 1.0420 | 0.9241 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7896.05 | 1.0506 | 1.1098 | 0.9241 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7896.05 | 1.0238 | 1.0516 | 0.9241 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7896.05 | 0.9953 | 0.9898 | 0.9241 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7896.05 | 0.1736 | -0.6994 | 0.9241 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7896.05 | 0.2150 | -0.6210 | 0.9241 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7896.05 | 0.2275 | -0.5971 | 0.9241 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7896.05 | 0.1673 | -0.7111 | 0.9241 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7896.05 | 0.1889 | -0.6705 | 0.9241 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9648.037 | 1.0001 | 1.0003 | 0.6971 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9648.037 | 1.0080 | 1.0230 | 0.6971 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9648.037 | 1.0452 | 1.1309 | 0.6971 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9648.037 | 0.7735 | 0.3836 | 0.6971 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9648.037 | 0.0961 | -0.9305 | 0.6971 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9648.037 | 0.1351 | -0.8868 | 0.6971 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9648.037 | 0.1497 | -0.8689 | 0.6971 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9648.037 | 0.1211 | -0.9033 | 0.6971 | |
| MDA-MB-361 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9648.037 | 0.1560 | -0.8609 | 0.6971 | |
| MDA-MB-415 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7897.037 | 0.9238 | 0.7930 | 0.7255 | |
| MDA-MB-415 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7897.037 | 0.9228 | 0.7904 | 0.7255 |