Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7919.04 | 0.0399 | -0.1553 | 3.7375 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7919.04 | 0.0264 | -0.2440 | 3.7375 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7919.04 | 0.0300 | -0.2173 | 3.7375 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7919.04 | 0.0455 | -0.1253 | 3.7375 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7919.04 | 0.0069 | -0.4725 | 3.7375 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7920.05 | 0.9689 | 0.9849 | 4.1624 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7920.05 | 1.0900 | 1.0418 | 4.1624 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7920.05 | 0.9633 | 0.9821 | 4.1624 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7920.05 | 0.8440 | 0.9201 | 4.1624 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7920.05 | 0.0687 | 0.0511 | 4.1624 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7920.05 | 0.0515 | -0.0192 | 4.1624 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7920.05 | 0.0556 | -0.0010 | 4.1624 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7920.05 | 0.0767 | 0.0794 | 4.1624 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7920.05 | 0.0289 | -0.1466 | 4.1624 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9042.05 | 0.9623 | 0.9755 | 3.1161 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9042.05 | 0.9442 | 0.9635 | 3.1161 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9042.05 | 0.6094 | 0.7061 | 3.1161 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9042.05 | 0.1878 | 0.1694 | 3.1161 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9042.05 | 0.0420 | -0.2771 | 3.1161 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9042.05 | 0.0583 | -0.1965 | 3.1161 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 9042.05 | 0.0636 | -0.1739 | 3.1161 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 9042.05 | 0.0846 | -0.0945 | 3.1161 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 9042.05 | 0.0390 | -0.2937 | 3.1161 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7921.04 | 0.9773 | 0.9414 | 0.7738 | |
| SUM185PE | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7921.04 | 0.9937 | 0.9837 | 0.7738 |