Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7917.05 | 0.0383 | -0.3839 | 2.7707 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7917.05 | 0.0412 | -0.3672 | 2.7707 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7917.05 | 0.0003 | -0.8935 | 2.7707 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9830.037 | 0.9669 | 0.9662 | 1.9735 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9830.037 | 1.0435 | 1.0436 | 1.9735 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9830.037 | 0.9183 | 0.9155 | 1.9735 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9830.037 | 1.0196 | 1.0197 | 1.9735 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9830.037 | 0.1101 | -0.3462 | 1.9735 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9830.037 | 0.0450 | -0.5845 | 1.9735 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 9830.037 | 0.0497 | -0.5629 | 1.9735 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 9830.037 | 0.0413 | -0.6023 | 1.9735 | |
| SUM149PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 9830.037 | 0.0119 | -0.7885 | 1.9735 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7918.037 | 1.0385 | 1.0263 | 2.8917 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7918.037 | 1.1819 | 1.1190 | 2.8917 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7918.037 | 0.8958 | 0.9253 | 2.8917 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7918.037 | 0.6592 | 0.7316 | 2.8917 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7918.037 | 0.0754 | -0.1818 | 2.8917 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7918.037 | 0.0572 | -0.2565 | 2.8917 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7918.037 | 0.0614 | -0.2379 | 2.8917 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7918.037 | 0.0607 | -0.2412 | 2.8917 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7918.037 | 0.1146 | -0.0546 | 2.8917 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7919.04 | 1.0106 | 1.0056 | 3.7375 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7919.04 | 0.9912 | 0.9953 | 3.7375 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7919.04 | 1.0033 | 1.0018 | 3.7375 | |
| SUM159PT | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7919.04 | 0.4882 | 0.6509 | 3.7375 |