Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.000128 | uM | 13009.002 | 1.0198 | 1.0294 | 1.3417 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.00064 | uM | 13009.002 | 0.9576 | 0.9365 | 1.3417 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.0032 | uM | 13009.002 | 0.9038 | 0.8548 | 1.3417 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.016 | uM | 13009.002 | 0.6455 | 0.4433 | 1.3417 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.08 | uM | 13009.002 | 0.3785 | -0.0305 | 1.3417 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.4 | uM | 13009.002 | 0.3742 | -0.0387 | 1.3417 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 2 | uM | 13009.002 | 0.3690 | -0.0486 | 1.3417 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 10 | uM | 13009.002 | 0.3581 | -0.0696 | 1.3417 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 13062.002 | 1.0166 | 1.0200 | 1.6470 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.000128 | uM | 13062.002 | 1.0601 | 1.0722 | 1.6470 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.00064 | uM | 13062.002 | 1.0032 | 1.0039 | 1.6470 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.0032 | uM | 13062.002 | 0.9143 | 0.8941 | 1.6470 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.016 | uM | 13062.002 | 0.5664 | 0.4163 | 1.6470 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.08 | uM | 13062.002 | 0.3537 | 0.0640 | 1.6470 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.4 | uM | 13062.002 | 0.3379 | 0.0349 | 1.6470 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 2 | uM | 13062.002 | 0.3557 | 0.0678 | 1.6470 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 10 | uM | 13062.002 | 0.3556 | 0.0675 | 1.6470 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9878.002 | 1.0200 | 1.0297 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9878.002 | 1.0081 | 1.0121 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9878.002 | 0.9088 | 0.8626 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9878.002 | 0.5729 | 0.3213 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9878.002 | 0.3485 | -0.0874 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9878.002 | 0.2169 | -0.3588 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9878.002 | 0.2163 | -0.3600 | 1.3437 | |
| SUM52PE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9878.002 | 0.2431 | -0.3020 | 1.3437 |