Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7921.002 | 0.9552 | 0.8761 | 0.7161 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 7921.002 | 0.8051 | 0.4775 | 0.7161 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 7921.002 | 0.5338 | -0.1677 | 0.7161 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 7921.002 | 0.6086 | -0.0004 | 0.7161 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 7921.002 | 0.6148 | 0.0138 | 0.7161 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 7921.002 | 0.6399 | 0.0722 | 0.7161 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10146.002 | 1.0986 | 1.2048 | 0.9649 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10146.002 | 0.8336 | 0.6562 | 0.9649 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10146.002 | 1.1618 | 1.3364 | 0.9649 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10146.002 | 1.0316 | 1.0655 | 0.9649 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 10146.002 | 0.9169 | 0.8281 | 0.9649 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 10146.002 | 0.7303 | 0.4440 | 0.9649 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 10146.002 | 0.7298 | 0.4430 | 0.9649 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 10146.002 | 0.8709 | 0.7330 | 0.9649 | |
| SUM185PE | TNBC | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 10146.002 | 0.8203 | 0.6289 | 0.9649 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9860.002 | 0.9919 | 0.9896 | 1.5734 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9860.002 | 1.0419 | 1.0529 | 1.5734 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9860.002 | 0.9931 | 0.9912 | 1.5734 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9860.002 | 0.7012 | 0.5961 | 1.5734 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.016 | uM | 9860.002 | 0.3298 | -0.0118 | 1.5734 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.08 | uM | 9860.002 | 0.2908 | -0.0877 | 1.5734 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.4 | uM | 9860.002 | 0.2883 | -0.0927 | 1.5734 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 2 | uM | 9860.002 | 0.2887 | -0.0921 | 1.5734 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 10 | uM | 9860.002 | 0.2676 | -0.1347 | 1.5734 | |
| SUM229PE | TNBC | - | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 13009.002 | 1.0057 | 1.0085 | 1.3417 |