Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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LY2 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 33.3 | uM | 10380.092 | 0.9648 | 0.9525 | 1.4888 | |
MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7482.091 | 0.9252 | 0.9214 | 1.9368 | |
MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7482.091 | 0.8230 | 0.8086 | 1.9368 | |
MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7482.091 | 0.8370 | 0.8244 | 1.9368 | |
MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7482.091 | 0.8115 | 0.7955 | 1.9368 | |
MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.107 | uM | 7482.091 | 0.5508 | 0.4700 | 1.9368 | |
MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 0.533 | uM | 7482.091 | 0.2881 | 0.0520 | 1.9368 | |
MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 2.67 | uM | 7482.091 | 0.4343 | 0.3003 | 1.9368 | |
MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 13.3 | uM | 7482.091 | 0.2720 | 0.0211 | 1.9368 | |
MB 157 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 66.7 | uM | 7482.091 | 0.1216 | -0.3261 | 1.9368 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7483.091 | 0.9813 | 0.9877 | 3.0465 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7483.091 | 0.9404 | 0.9601 | 3.0465 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7483.091 | 0.9527 | 0.9685 | 3.0465 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7483.091 | 0.9874 | 0.9917 | 3.0465 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.107 | uM | 7483.091 | 0.9627 | 0.9752 | 3.0465 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.533 | uM | 7483.091 | 0.7774 | 0.8413 | 3.0465 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 2.67 | uM | 7483.091 | 0.3781 | 0.4534 | 3.0465 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 13.3 | uM | 7483.091 | 0.1193 | -0.0049 | 3.0465 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 66.7 | uM | 7483.091 | 0.1007 | -0.0587 | 3.0465 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7484.09 | 0.9451 | 0.9579 | 2.6525 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7484.09 | 0.9806 | 0.9853 | 2.6525 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7484.09 | 0.9257 | 0.9427 | 2.6525 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7484.09 | 1.0172 | 1.0129 | 2.6525 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.107 | uM | 7484.09 | 0.8374 | 0.8706 | 2.6525 | |
MCF 10A | NM | Basal B | Erlotinib | EGFR | ErbB | 0.533 | uM | 7484.09 | 0.6358 | 0.6861 | 2.6525 |