Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
LY2
HR+
Luminal
Erlotinib
EGFR
ErbB
33.3
uM
10380.092
0.9648 0.9525 1.4888
MB 157
Unknown
Unknown
Erlotinib
EGFR
ErbB
0.000171
uM
7482.091
0.9252 0.9214 1.9368
MB 157
Unknown
Unknown
Erlotinib
EGFR
ErbB
0.000853
uM
7482.091
0.8230 0.8086 1.9368
MB 157
Unknown
Unknown
Erlotinib
EGFR
ErbB
0.00427
uM
7482.091
0.8370 0.8244 1.9368
MB 157
Unknown
Unknown
Erlotinib
EGFR
ErbB
0.0213
uM
7482.091
0.8115 0.7955 1.9368
MB 157
Unknown
Unknown
Erlotinib
EGFR
ErbB
0.107
uM
7482.091
0.5508 0.4700 1.9368
MB 157
Unknown
Unknown
Erlotinib
EGFR
ErbB
0.533
uM
7482.091
0.2881 0.0520 1.9368
MB 157
Unknown
Unknown
Erlotinib
EGFR
ErbB
2.67
uM
7482.091
0.4343 0.3003 1.9368
MB 157
Unknown
Unknown
Erlotinib
EGFR
ErbB
13.3
uM
7482.091
0.2720 0.0211 1.9368
MB 157
Unknown
Unknown
Erlotinib
EGFR
ErbB
66.7
uM
7482.091
0.1216 -0.3261 1.9368
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.000171
uM
7483.091
0.9813 0.9877 3.0465
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.000853
uM
7483.091
0.9404 0.9601 3.0465
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.00427
uM
7483.091
0.9527 0.9685 3.0465
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.0213
uM
7483.091
0.9874 0.9917 3.0465
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.107
uM
7483.091
0.9627 0.9752 3.0465
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.533
uM
7483.091
0.7774 0.8413 3.0465
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
2.67
uM
7483.091
0.3781 0.4534 3.0465
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
13.3
uM
7483.091
0.1193 -0.0049 3.0465
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
66.7
uM
7483.091
0.1007 -0.0587 3.0465
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.000171
uM
7484.09
0.9451 0.9579 2.6525
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.000853
uM
7484.09
0.9806 0.9853 2.6525
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.00427
uM
7484.09
0.9257 0.9427 2.6525
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.0213
uM
7484.09
1.0172 1.0129 2.6525
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.107
uM
7484.09
0.8374 0.8706 2.6525
MCF 10A
NM
Basal B
Erlotinib
EGFR
ErbB
0.533
uM
7484.09
0.6358 0.6861 2.6525