Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 10266.037 | 0.5386 | -0.1050 | 0.7695 | |
| MDA-MB-436 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 10266.037 | 0.1693 | -0.8011 | 0.7695 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7903.04 | 0.9875 | 0.9792 | 1.2080 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7903.04 | 0.9838 | 0.9731 | 1.2080 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7903.04 | 0.9829 | 0.9716 | 1.2080 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7903.04 | 0.8203 | 0.6976 | 1.2080 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7903.04 | 0.1944 | -0.4845 | 1.2080 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7903.04 | 0.2160 | -0.4375 | 1.2080 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7903.04 | 0.2182 | -0.4328 | 1.2080 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7903.04 | 0.2026 | -0.4666 | 1.2080 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7903.04 | 0.0754 | -0.7647 | 1.2080 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9708.037 | 1.0417 | 1.0735 | 1.1319 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9708.037 | 1.0542 | 1.0954 | 1.1319 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9708.037 | 0.9688 | 0.9448 | 1.1319 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9708.037 | 0.6973 | 0.4544 | 1.1319 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9708.037 | 0.2192 | -0.4767 | 1.1319 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9708.037 | 0.2414 | -0.4303 | 1.1319 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9708.037 | 0.2460 | -0.4208 | 1.1319 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9708.037 | 0.1954 | -0.5272 | 1.1319 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9708.037 | 0.0153 | -0.9502 | 1.1319 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9723.037 | 1.1534 | 1.2957 | 1.0349 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9723.037 | 1.1465 | 1.2824 | 1.0349 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9723.037 | 1.0697 | 1.1345 | 1.0349 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9723.037 | 1.1442 | 1.2780 | 1.0349 | |
| MDA-MB-453 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9723.037 | 0.1898 | -0.5986 | 1.0349 |