Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.0000853 | uM | 10755.146 | 0.9523 | 0.8819 | 0.8035 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.000427 | uM | 10755.146 | 0.9530 | 0.8838 | 0.8035 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.00213 | uM | 10755.146 | 0.9579 | 0.8958 | 0.8035 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.0107 | uM | 10755.146 | 0.9814 | 0.9538 | 0.8035 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.0533 | uM | 10755.146 | 0.9540 | 0.8862 | 0.8035 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.267 | uM | 10755.146 | 0.9760 | 0.9404 | 0.8035 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 1.33 | uM | 10755.146 | 0.9711 | 0.9284 | 0.8035 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 6.67 | uM | 10755.146 | 0.9681 | 0.9209 | 0.8035 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 33.3 | uM | 10755.146 | 0.7872 | 0.4848 | 0.8035 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.0000853 | uM | 12070.155 | 0.9545 | 0.9222 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.000427 | uM | 12070.155 | 0.9816 | 0.9685 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.00213 | uM | 12070.155 | 1.0362 | 1.0616 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.0107 | uM | 12070.155 | 1.0531 | 1.0901 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.0533 | uM | 12070.155 | 0.9324 | 0.8841 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 0.267 | uM | 12070.155 | 0.6784 | 0.4366 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 1.33 | uM | 12070.155 | 0.3040 | -0.2753 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 6.67 | uM | 12070.155 | 0.7785 | 0.6155 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | Dactolisib | PI3K | PI3K | 33.3 | uM | 12070.155 | 0.6602 | 0.4037 | 1.1729 | |
| HCC1143 | TNBC | Basal A | Dactolisib | PI3K | PI3K | 0.0000853 | uM | 12112.155 | 0.9929 | 0.9921 | 1.7965 | |
| HCC1143 | TNBC | Basal A | Dactolisib | PI3K | PI3K | 0.000427 | uM | 12112.155 | 0.9707 | 0.9671 | 1.7965 | |
| HCC1143 | TNBC | Basal A | Dactolisib | PI3K | PI3K | 0.00213 | uM | 12112.155 | 0.9317 | 0.9228 | 1.7965 | |
| HCC1143 | TNBC | Basal A | Dactolisib | PI3K | PI3K | 0.0107 | uM | 12112.155 | 0.9772 | 0.9745 | 1.7965 | |
| HCC1143 | TNBC | Basal A | Dactolisib | PI3K | PI3K | 0.0533 | uM | 12112.155 | 0.8788 | 0.8612 | 1.7965 | |
| HCC1143 | TNBC | Basal A | Dactolisib | PI3K | PI3K | 0.267 | uM | 12112.155 | 0.8004 | 0.7669 | 1.7965 | |
| HCC1143 | TNBC | Basal A | Dactolisib | PI3K | PI3K | 1.33 | uM | 12112.155 | 0.3309 | 0.0806 | 1.7965 |