Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 7841.077 | 1.0674 | 1.3137 | 0.4474 | |
| HCC202 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 7841.077 | 0.9717 | 0.8756 | 0.4474 | |
| HCC202 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 7841.077 | 1.0375 | 1.1717 | 0.4474 | |
| HCC202 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 7841.077 | 1.0632 | 1.2937 | 0.4474 | |
| HCC202 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 7841.077 | 0.8921 | 0.5495 | 0.4474 | |
| HCC202 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 7841.077 | 0.5898 | -0.3854 | 0.4474 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.000189 | uM | 7849.007 | 0.9635 | 0.8362 | 0.4353 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.000945 | uM | 7849.007 | 1.0629 | 1.3006 | 0.4353 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.00472 | uM | 7849.007 | 1.0672 | 1.3221 | 0.4353 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.0236 | uM | 7849.007 | 1.0077 | 1.0357 | 0.4353 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.118 | uM | 7849.007 | 0.9939 | 0.9720 | 0.4353 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.59 | uM | 7849.007 | 0.9753 | 0.8885 | 0.4353 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 2.95 | uM | 7849.007 | 0.9194 | 0.6490 | 0.4353 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 14.8 | uM | 7849.007 | 0.8602 | 0.4153 | 0.4353 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 73.8 | uM | 7849.007 | 0.7259 | -0.0418 | 0.4353 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.000189 | uM | 7849.043 | 1.0114 | 1.0659 | 0.3502 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.000945 | uM | 7849.043 | 0.9840 | 0.9100 | 0.3502 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.00472 | uM | 7849.043 | 1.0168 | 1.0975 | 0.3502 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.0236 | uM | 7849.043 | 1.0040 | 1.0231 | 0.3502 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.118 | uM | 7849.043 | 1.0163 | 1.0943 | 0.3502 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.59 | uM | 7849.043 | 1.0134 | 1.0774 | 0.3502 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 2.95 | uM | 7849.043 | 1.0066 | 1.0381 | 0.3502 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 14.8 | uM | 7849.043 | 0.9916 | 0.9524 | 0.3502 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 73.8 | uM | 7849.043 | 0.9415 | 0.6838 | 0.3502 | |
| HCC2185 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.000189 | uM | 9421.034 | 0.9984 | 0.9948 | 0.6220 |