Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9278.121 | 1.0399 | 1.1819 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9278.121 | 1.0402 | 1.1832 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 9278.121 | 1.0367 | 1.1669 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 9278.121 | 1.0531 | 1.2440 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 9278.121 | 0.9593 | 0.8236 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 9278.121 | 0.9219 | 0.6690 | 0.4498 | |
| HCC1419 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 9278.121 | 0.5580 | -0.4534 | 0.4498 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9294.121 | 1.0220 | 1.0589 | 0.7502 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9294.121 | 0.9603 | 0.8948 | 0.7502 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9294.121 | 0.9939 | 0.9838 | 0.7502 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9294.121 | 1.0366 | 1.0981 | 0.7502 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 9294.121 | 1.0104 | 1.0278 | 0.7502 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 9294.121 | 1.0725 | 1.1957 | 0.7502 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 9294.121 | 1.0092 | 1.0246 | 0.7502 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 9294.121 | 0.7815 | 0.4397 | 0.7502 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 9294.121 | 0.2428 | -0.6969 | 0.7502 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9299.121 | 1.0239 | 1.1179 | 0.4126 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9299.121 | 1.0394 | 1.1965 | 0.4126 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9299.121 | 1.0838 | 1.4305 | 0.4126 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9299.121 | 1.0378 | 1.1880 | 0.4126 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 9299.121 | 1.0689 | 1.3508 | 0.4126 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 9299.121 | 1.0670 | 1.3404 | 0.4126 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 9299.121 | 0.9807 | 0.9075 | 0.4126 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 9299.121 | 0.9507 | 0.7693 | 0.4126 | |
| HCC1428 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 9299.121 | 0.4643 | -0.6885 | 0.4126 |