Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7876.017 | 0.6736 | 0.1095 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7876.017 | 1.1645 | 1.5100 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7876.017 | 1.1836 | 1.5715 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7876.017 | 0.6892 | 0.1480 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7876.017 | 1.1792 | 1.5572 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7876.017 | 0.4378 | -0.4164 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7876.017 | 0.5232 | -0.2388 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7876.017 | 0.0865 | -0.9480 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7877.017 | 1.0550 | 1.1600 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7877.017 | 1.0013 | 1.0038 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7877.017 | 1.0309 | 1.0894 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7877.017 | 1.0143 | 1.0411 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7877.017 | 1.0558 | 1.1625 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7877.017 | 0.9990 | 0.9971 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7877.017 | 0.9896 | 0.9700 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7877.017 | 0.7594 | 0.3464 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7877.017 | 0.5628 | -0.1249 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00128 | uM | 10077.049 | 1.1294 | 1.5015 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0064 | uM | 10077.049 | 0.9155 | 0.7004 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.032 | uM | 10077.049 | 1.1433 | 1.5582 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.16 | uM | 10077.049 | 1.0129 | 1.0475 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.8 | uM | 10077.049 | 1.1129 | 1.4346 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 4 | uM | 10077.049 | 1.0499 | 1.1874 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 20 | uM | 10077.049 | 1.0618 | 1.2330 | 0.5440 | |
| MDA-MB-134-VI | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 100 | uM | 10077.049 | 1.2139 | 1.8563 | 0.5440 |