Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10262.021 | 1.1077 | 1.3242 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10262.021 | 1.0537 | 1.1597 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10262.021 | 1.0626 | 1.1866 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10262.021 | 0.9398 | 0.8256 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10262.021 | 1.0084 | 1.0249 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10262.021 | 0.9730 | 0.9213 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10262.021 | 0.5975 | -0.0616 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10262.021 | 0.2505 | -0.7383 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10262.021 | 0.0908 | -0.9411 | 0.6806 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7837.017 | 1.1249 | 1.1721 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7837.017 | 1.0280 | 1.0391 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7837.017 | 1.0601 | 1.0836 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7837.017 | 1.0621 | 1.0864 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7837.017 | 1.0676 | 1.0939 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7837.017 | 0.8578 | 0.7960 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7837.017 | 0.5994 | 0.3967 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7837.017 | 0.0622 | -0.7150 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7837.017 | 0.0166 | -0.8874 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9386.017 | 0.9946 | 0.9920 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9386.017 | 0.9691 | 0.9545 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9386.017 | 1.0498 | 1.0724 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9386.017 | 0.9754 | 0.9639 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9386.017 | 0.9772 | 0.9665 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9386.017 | 0.8534 | 0.7810 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9386.017 | 0.3255 | -0.1202 | 1.3666 |