Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7832.017 | 0.9752 | 0.9629 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7832.017 | 0.9868 | 0.9802 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7832.017 | 1.0046 | 1.0069 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7832.017 | 0.8389 | 0.7543 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7832.017 | 0.1747 | -0.4559 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7832.017 | 0.0612 | -0.7513 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7832.017 | 0.0314 | -0.8487 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7833.017 | 1.0049 | 1.0075 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7833.017 | 0.9765 | 0.9637 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7833.017 | 1.0279 | 1.0428 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7833.017 | 1.0089 | 1.0137 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7833.017 | 0.9915 | 0.9868 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7833.017 | 0.9230 | 0.8801 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7833.017 | 0.6686 | 0.4665 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7833.017 | 0.5673 | 0.2921 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7833.017 | 1.0092 | 1.0141 | 1.2975 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7834.13 | 1.0025 | 1.0026 | 1.9535 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7834.13 | 0.9938 | 0.9937 | 1.9535 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7834.13 | 0.9504 | 0.9486 | 1.9535 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7834.13 | 0.9921 | 0.9919 | 1.9535 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7834.13 | 0.9051 | 0.9005 | 1.9535 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7834.13 | 0.7817 | 0.7631 | 1.9535 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7834.13 | 0.2199 | -0.0788 | 1.9535 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7834.13 | 0.0889 | -0.4206 | 1.9535 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7834.13 | 0.0305 | -0.6646 | 1.9535 |