Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7808.017 | 1.0909 | 1.0733 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7808.017 | 0.9657 | 0.9713 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7808.017 | 1.0213 | 1.0175 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7808.017 | 0.9418 | 0.9510 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7808.017 | 0.5493 | 0.5609 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7808.017 | 0.0083 | -0.7242 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7808.017 | 0.0005 | -0.9142 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9226.021 | 1.0067 | 1.0053 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9226.021 | 1.0018 | 1.0014 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9226.021 | 1.0243 | 1.0192 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9226.021 | 0.9653 | 0.9721 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9226.021 | 0.9950 | 0.9960 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9226.021 | 0.9240 | 0.9381 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9226.021 | 0.4110 | 0.4042 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9226.021 | 0.0180 | -0.5957 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9226.021 | 0.0093 | -0.6894 | 2.5142 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7809.017 | 0.9126 | 0.8987 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7809.017 | 0.9802 | 0.9774 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7809.017 | 0.9259 | 0.9143 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7809.017 | 0.8821 | 0.8623 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7809.017 | 0.9255 | 0.9139 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7809.017 | 0.8095 | 0.7736 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7809.017 | 0.5549 | 0.4309 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7809.017 | 0.1275 | -0.3798 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7809.017 | 0.0655 | -0.5754 | 1.7591 |