Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7810.017 | 1.0637 | 1.1422 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7810.017 | 1.0309 | 1.0688 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7810.017 | 1.0610 | 1.1361 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7810.017 | 1.0189 | 1.0421 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7810.017 | 1.0980 | 1.2192 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7810.017 | 0.9755 | 0.9455 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7810.017 | 0.7412 | 0.4331 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7810.017 | 0.0744 | -0.8890 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7810.017 | 0.0227 | -0.9703 | 0.8986 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00128 | uM | 9233.049 | 1.0656 | 1.1200 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0064 | uM | 9233.049 | 1.0092 | 1.0168 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.032 | uM | 9233.049 | 1.1287 | 1.2346 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.16 | uM | 9233.049 | 0.9986 | 0.9974 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.8 | uM | 9233.049 | 1.0607 | 1.1109 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 4 | uM | 9233.049 | 1.0402 | 1.0736 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 20 | uM | 9233.049 | 1.0458 | 1.0838 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 100 | uM | 9233.049 | 1.0861 | 1.1572 | 1.0911 | |
| HCC1143 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 500 | uM | 9233.049 | 1.0063 | 1.0116 | 1.0911 | |
| HCC1187 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7811.017 | 1.0802 | 1.4776 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7811.017 | 0.6729 | -0.3338 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7811.017 | 1.0644 | 1.3780 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7811.017 | 0.9767 | 0.8733 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7811.017 | 0.9681 | 0.8278 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7811.017 | 0.8603 | 0.3172 | 0.3604 | |
| HCC1187 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7811.017 | 0.0972 | -0.9969 | 0.3604 |