Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Chloroquine | 0.106 | uM | 12989.177 | 0.7583 | -0.0408 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | Chloroquine | 0.532 | uM | 12989.177 | 0.7140 | -0.1825 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | Chloroquine | 2.66 | uM | 12989.177 | 0.9335 | 0.6657 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | Chloroquine | 13.3 | uM | 12989.177 | 0.6192 | -0.4401 | 0.3765 | |||
| MDA-MB-361 | HER2amp | Luminal | Chloroquine | 66.5 | uM | 12989.177 | 0.0004 | -1.0000 | 0.3765 | |||
| MDA-MB-415 | HR+ | Luminal | Chloroquine | 0.00017 | uM | 12959.177 | 0.9904 | 0.9654 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | Chloroquine | 0.000851 | uM | 12959.177 | 0.9940 | 0.9784 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | Chloroquine | 0.00426 | uM | 12959.177 | 0.9917 | 0.9699 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | Chloroquine | 0.0213 | uM | 12959.177 | 0.8723 | 0.5628 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | Chloroquine | 0.106 | uM | 12959.177 | 0.9600 | 0.8579 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | Chloroquine | 0.532 | uM | 12959.177 | 0.9589 | 0.8539 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | Chloroquine | 2.66 | uM | 12959.177 | 0.9444 | 0.8037 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | Chloroquine | 13.3 | uM | 12959.177 | 0.5945 | -0.2180 | 0.5538 | |||
| MDA-MB-415 | HR+ | Luminal | Chloroquine | 66.5 | uM | 12959.177 | 0.0117 | -0.9994 | 0.5538 | |||
| MDA-MB-453 | TNBC | Luminal | Chloroquine | 0.00017 | uM | 12964.177 | 0.9776 | 0.9405 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | Chloroquine | 0.000851 | uM | 12964.177 | 0.9405 | 0.8429 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | Chloroquine | 0.00426 | uM | 12964.177 | 0.9213 | 0.7929 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | Chloroquine | 0.0213 | uM | 12964.177 | 0.8389 | 0.5820 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | Chloroquine | 0.106 | uM | 12964.177 | 0.9699 | 0.9202 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | Chloroquine | 0.532 | uM | 12964.177 | 0.8683 | 0.6564 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | Chloroquine | 2.66 | uM | 12964.177 | 0.7474 | 0.3562 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | Chloroquine | 13.3 | uM | 12964.177 | 0.3087 | -0.5832 | 0.7495 | |||
| MDA-MB-453 | TNBC | Luminal | Chloroquine | 66.5 | uM | 12964.177 | 0.0099 | -0.9958 | 0.7495 | |||
| MX1 | Unknown | Unknown | Chloroquine | 0.00017 | uM | 12667.177 | 1.0553 | 1.1912 | 0.5892 | |||
| MX1 | Unknown | Unknown | Chloroquine | 0.000851 | uM | 12667.177 | 1.0055 | 1.0187 | 0.5892 |