Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9933.034 | 0.8763 | 0.5806 | 0.5612 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9933.034 | 1.1576 | 1.5959 | 0.5612 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9933.034 | 0.8046 | 0.3578 | 0.5612 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9933.034 | 0.9751 | 0.9122 | 0.5612 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9933.034 | 0.9110 | 0.6940 | 0.5612 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9933.034 | 0.9758 | 0.9145 | 0.5612 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9933.034 | 0.9816 | 0.9348 | 0.5612 | ||
| UACC-893 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9933.034 | 0.4996 | -0.4193 | 0.5612 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.00128 | uM | 7932.052 | 1.0663 | 1.1500 | 0.8877 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0064 | uM | 7932.052 | 0.9810 | 0.9573 | 0.8877 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.032 | uM | 7932.052 | 1.1051 | 1.2384 | 0.8877 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.16 | uM | 7932.052 | 1.0088 | 1.0197 | 0.8877 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.8 | uM | 7932.052 | 1.0217 | 1.0490 | 0.8877 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 4 | uM | 7932.052 | 0.8401 | 0.6436 | 0.8877 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 20 | uM | 7932.052 | 0.8337 | 0.6295 | 0.8877 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 100 | uM | 7932.052 | 0.7994 | 0.5541 | 0.8877 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 500 | uM | 7932.052 | 0.7389 | 0.4224 | 0.8877 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9958.034 | 1.0137 | 1.0529 | 0.5217 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9958.034 | 0.9712 | 0.8909 | 0.5217 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9958.034 | 0.9865 | 0.9487 | 0.5217 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9958.034 | 0.9270 | 0.7297 | 0.5217 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9958.034 | 0.8511 | 0.4684 | 0.5217 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9958.034 | 0.8510 | 0.4681 | 0.5217 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9958.034 | 0.8203 | 0.3680 | 0.5217 | ||
| ZR-75-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9958.034 | 0.7537 | 0.1630 | 0.5217 |