Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7809.016 | 0.8860 | 0.8595 | 1.6622 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7810.016 | 1.0686 | 1.1525 | 0.9032 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7810.016 | 0.9983 | 0.9962 | 0.9032 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7810.016 | 1.0478 | 1.1061 | 0.9032 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7810.016 | 1.0180 | 1.0400 | 0.9032 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7810.016 | 1.0717 | 1.1593 | 0.9032 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7810.016 | 1.0312 | 1.0692 | 0.9032 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7810.016 | 1.0581 | 1.1291 | 0.9032 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7810.016 | 1.0374 | 1.0830 | 0.9032 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7810.016 | 0.7380 | 0.4286 | 0.9032 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7811.044 | 1.0449 | 1.3073 | 0.3073 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7811.044 | 0.9926 | 0.9525 | 0.3073 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7811.044 | 1.0677 | 1.4749 | 0.3073 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7811.044 | 1.0368 | 1.2497 | 0.3073 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7811.044 | 1.0486 | 1.3342 | 0.3073 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7811.044 | 1.0330 | 1.2232 | 0.3073 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7811.044 | 0.9852 | 0.9054 | 0.3073 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7811.044 | 0.4537 | -0.8472 | 0.3073 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7811.044 | 0.0124 | -1.0000 | 0.3073 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7812.016 | 1.0139 | 1.0262 | 1.0628 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7812.016 | 0.9892 | 0.9797 | 1.0628 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7812.016 | 1.0507 | 1.0954 | 1.0628 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7812.016 | 0.9400 | 0.8869 | 1.0628 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7812.016 | 0.9781 | 0.9587 | 1.0628 | ||
| HCC1187 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7812.016 | 0.9425 | 0.8915 | 1.0628 |