Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7807.016 | 0.9476 | 0.9506 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7807.016 | 0.9478 | 0.9508 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7807.016 | 0.9697 | 0.9716 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7807.016 | 0.9252 | 0.9290 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7807.016 | 0.9831 | 0.9842 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7807.016 | 0.8955 | 0.9000 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7807.016 | 0.0177 | -0.6933 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7807.016 | 0.0055 | -0.8212 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7808.016 | 1.2151 | 1.1817 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7808.016 | 0.9843 | 0.9860 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7808.016 | 1.1398 | 1.1203 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7808.016 | 1.0600 | 1.0527 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7808.016 | 1.0587 | 1.0516 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7808.016 | 1.0250 | 1.0221 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7808.016 | 1.1717 | 1.1466 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7808.016 | 0.5467 | 0.5274 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7808.016 | 0.8898 | 0.8985 | 2.2401 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7809.016 | 1.0398 | 1.0475 | 1.6622 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7809.016 | 0.9544 | 0.9446 | 1.6622 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7809.016 | 0.9895 | 0.9874 | 1.6622 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7809.016 | 0.9196 | 0.9017 | 1.6622 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7809.016 | 0.9221 | 0.9048 | 1.6622 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7809.016 | 0.9081 | 0.8873 | 1.6622 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7809.016 | 0.8323 | 0.7909 | 1.6622 | ||
| HCC1143 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7809.016 | 0.5432 | 0.3854 | 1.6622 |