Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
AU565
HER2amp
Luminal
5-DFUR
TYMS
TYMS
5000
uM
10880.143
0.2530 -0.1493 1.6077
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
0.0128
uM
10581.143
0.8773 0.7309 0.9062
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
0.064
uM
10581.143
0.8607 0.6948 0.9062
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
0.32
uM
10581.143
0.9419 0.8722 0.9062
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
1.6
uM
10581.143
0.9518 0.8940 0.9062
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
8
uM
10581.143
1.0124 1.0273 0.9062
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
40
uM
10581.143
0.8364 0.6422 0.9062
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
200
uM
10581.143
0.8042 0.5724 0.9062
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
1000
uM
10581.143
0.5903 0.1180 0.9062
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
5000
uM
10581.143
0.4492 -0.1731 0.9062
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
0.0128
uM
11854.143
0.9547 0.9187 1.1185
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
0.064
uM
11854.143
1.0002 1.0003 1.1185
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
0.32
uM
11854.143
0.9898 0.9817 1.1185
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
1.6
uM
11854.143
0.9707 0.9475 1.1185
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
8
uM
11854.143
0.9550 0.9193 1.1185
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
40
uM
11854.143
0.8955 0.8120 1.1185
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
200
uM
11854.143
0.8024 0.6427 1.1185
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
1000
uM
11854.143
0.6272 0.3180 1.1185
BT-20
TNBC
Basal A
5-DFUR
TYMS
TYMS
5000
uM
11854.143
0.5289 0.1316 1.1185
BT-474
HER2amp
Luminal
5-DFUR
TYMS
TYMS
0.0128
uM
12056.143
0.9503 0.9013 1.0075
BT-474
HER2amp
Luminal
5-DFUR
TYMS
TYMS
0.064
uM
12056.143
0.9167 0.8346 1.0075
BT-474
HER2amp
Luminal
5-DFUR
TYMS
TYMS
0.32
uM
12056.143
0.9479 0.8965 1.0075
BT-474
HER2amp
Luminal
5-DFUR
TYMS
TYMS
1.6
uM
12056.143
0.9510 0.9027 1.0075
BT-474
HER2amp
Luminal
5-DFUR
TYMS
TYMS
8
uM
12056.143
0.9712 0.9427 1.0075
BT-474
HER2amp
Luminal
5-DFUR
TYMS
TYMS
40
uM
12056.143
0.8544 0.7108 1.0075