Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12566.143 | 0.9531 | 0.9423 | 1.6413 | |
| 184B5 | NM | Basal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12566.143 | 0.9628 | 0.9543 | 1.6413 | |
| 184B5 | NM | Basal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12566.143 | 0.9166 | 0.8966 | 1.6413 | |
| 184B5 | NM | Basal | 5-DFUR | TYMS | TYMS | 8 | uM | 12566.143 | 0.8415 | 0.8004 | 1.6413 | |
| 184B5 | NM | Basal | 5-DFUR | TYMS | TYMS | 40 | uM | 12566.143 | 0.7683 | 0.7032 | 1.6413 | |
| 184B5 | NM | Basal | 5-DFUR | TYMS | TYMS | 200 | uM | 12566.143 | 0.6535 | 0.5433 | 1.6413 | |
| 184B5 | NM | Basal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12566.143 | 0.5604 | 0.4053 | 1.6413 | |
| 184B5 | NM | Basal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12566.143 | 0.4040 | 0.1514 | 1.6413 | |
| 600MPE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12224.143 | 0.9826 | 0.9584 | 0.8349 | |
| 600MPE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12224.143 | 0.9673 | 0.9220 | 0.8349 | |
| 600MPE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12224.143 | 0.8517 | 0.6501 | 0.8349 | |
| 600MPE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12224.143 | 0.6978 | 0.2998 | 0.8349 | |
| 600MPE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 12224.143 | 0.6358 | 0.1626 | 0.8349 | |
| 600MPE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 12224.143 | 0.6315 | 0.1533 | 0.8349 | |
| 600MPE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12224.143 | 0.5902 | 0.0635 | 0.8349 | |
| 600MPE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12224.143 | 0.5729 | 0.0262 | 0.8349 | |
| 600MPE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12224.143 | 0.3844 | -0.3636 | 0.8349 | |
| AU565 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10880.143 | 0.9971 | 0.9964 | 1.6077 | |
| AU565 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10880.143 | 0.9607 | 0.9508 | 1.6077 | |
| AU565 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10880.143 | 0.9956 | 0.9945 | 1.6077 | |
| AU565 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10880.143 | 0.7379 | 0.6554 | 1.6077 | |
| AU565 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10880.143 | 0.5299 | 0.3474 | 1.6077 | |
| AU565 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10880.143 | 0.5619 | 0.3973 | 1.6077 | |
| AU565 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10880.143 | 0.5432 | 0.3683 | 1.6077 | |
| AU565 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10880.143 | 0.4368 | 0.1947 | 1.6077 |