Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | 2-deoxyglucose | 1.07 | uM | 13070.177 | 0.8871 | 0.7518 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | 2-deoxyglucose | 5.33 | uM | 13070.177 | 0.8533 | 0.6780 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | 2-deoxyglucose | 26.7 | uM | 13070.177 | 0.7894 | 0.5395 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | 2-deoxyglucose | 133 | uM | 13070.177 | 0.8537 | 0.6790 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | 2-deoxyglucose | 667 | uM | 13070.177 | 0.5731 | 0.0803 | 0.9040 | |||
| T47DKBLUC | Unknown | Unknown | 2-deoxyglucose | 3330 | uM | 13070.177 | 0.6872 | 0.3207 | 0.9040 | |||
| ZR-75-1 | HR+ | Luminal | 2-deoxyglucose | 0.00853 | uM | 12677.177 | 0.8142 | 0.6449 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | 2-deoxyglucose | 0.0427 | uM | 12677.177 | 0.9374 | 0.8808 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | 2-deoxyglucose | 0.213 | uM | 12677.177 | 0.9744 | 0.9512 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | 2-deoxyglucose | 1.07 | uM | 12677.177 | 0.8576 | 0.7282 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | 2-deoxyglucose | 5.33 | uM | 12677.177 | 1.0006 | 1.0010 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | 2-deoxyglucose | 26.7 | uM | 12677.177 | 0.9032 | 0.8153 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | 2-deoxyglucose | 133 | uM | 12677.177 | 0.8715 | 0.7549 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | 2-deoxyglucose | 667 | uM | 12677.177 | 0.8362 | 0.6872 | 1.0515 | |||
| ZR-75-1 | HR+ | Luminal | 2-deoxyglucose | 3330 | uM | 12677.177 | 0.6839 | 0.3935 | 1.0515 | |||
| 184A1 | NM | Basal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12509.143 | 1.0576 | 1.0853 | 1.3392 | |
| 184A1 | NM | Basal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12509.143 | 1.0070 | 1.0104 | 1.3392 | |
| 184A1 | NM | Basal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12509.143 | 1.0571 | 1.0846 | 1.3392 | |
| 184A1 | NM | Basal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12509.143 | 1.0174 | 1.0259 | 1.3392 | |
| 184A1 | NM | Basal | 5-DFUR | TYMS | TYMS | 8 | uM | 12509.143 | 0.9222 | 0.8826 | 1.3392 | |
| 184A1 | NM | Basal | 5-DFUR | TYMS | TYMS | 40 | uM | 12509.143 | 0.8213 | 0.7265 | 1.3392 | |
| 184A1 | NM | Basal | 5-DFUR | TYMS | TYMS | 200 | uM | 12509.143 | 0.6536 | 0.4559 | 1.3392 | |
| 184A1 | NM | Basal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12509.143 | 0.5790 | 0.3300 | 1.3392 | |
| 184A1 | NM | Basal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12509.143 | 0.2735 | -0.2404 | 1.3392 | |
| 184B5 | NM | Basal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12566.143 | 0.9447 | 0.9318 | 1.6413 |