Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 7860.042 | 0.8871 | 0.6742 | 0.6736 | |
| HCC70 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9501.026 | 1.0847 | 1.2254 | 0.7616 | |
| HCC70 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9501.026 | 1.1286 | 1.3443 | 0.7616 | |
| HCC70 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9501.026 | 1.0074 | 1.0194 | 0.7616 | |
| HCC70 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9501.026 | 1.1942 | 1.5250 | 0.7616 | |
| HCC70 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9501.026 | 1.0404 | 1.1067 | 0.7616 | |
| HCC70 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9501.026 | 0.9548 | 0.8820 | 0.7616 | |
| HCC70 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9501.026 | 0.8723 | 0.6716 | 0.7616 | |
| HCC70 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 9501.026 | 0.8928 | 0.7232 | 0.7616 | |
| HCC70 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 9501.026 | 0.8002 | 0.4925 | 0.7616 | |
| HMT-3522 S1 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7911.018 | 0.9735 | 0.9713 | 1.8543 | |
| HMT-3522 S1 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7911.018 | 0.9903 | 0.9895 | 1.8543 | |
| HMT-3522 S1 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7911.018 | 0.9567 | 0.9528 | 1.8543 | |
| HMT-3522 S1 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7911.018 | 1.0143 | 1.0154 | 1.8543 | |
| HMT-3522 S1 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7911.018 | 0.8778 | 0.8643 | 1.8543 | |
| HMT-3522 S1 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7911.018 | 0.7906 | 0.7620 | 1.8543 | |
| HMT-3522 S1 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7911.018 | 0.5975 | 0.5151 | 1.8543 | |
| HMT-3522 S1 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.137 | uM | 7911.018 | 0.4153 | 0.2452 | 1.8543 | |
| HMT-3522 S1 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.685 | uM | 7911.018 | 0.3856 | 0.1964 | 1.8543 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7861.018 | 2.1121 | 3.8273 | 0.8485 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7861.018 | 2.1567 | 3.9477 | 0.8485 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7861.018 | 2.0354 | 3.6215 | 0.8485 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7861.018 | 2.3084 | 4.3604 | 0.8485 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7861.018 | 2.2508 | 4.2031 | 0.8485 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7861.018 | 2.1912 | 4.0411 | 0.8485 |