Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7861.018 | 2.1345 | 3.8877 | 0.8485 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7861.018 | 2.0733 | 3.7230 | 0.8485 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7861.018 | 2.1504 | 3.9307 | 0.8485 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7862.042 | 0.9389 | 0.9035 | 1.2756 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7862.042 | 0.9488 | 0.9193 | 1.2756 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7862.042 | 0.9877 | 0.9806 | 1.2756 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7862.042 | 1.0455 | 1.0710 | 1.2756 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7862.042 | 0.9406 | 0.9063 | 1.2756 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7862.042 | 1.0003 | 1.0004 | 1.2756 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7862.042 | 1.0078 | 1.0122 | 1.2756 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7862.042 | 0.9952 | 0.9924 | 1.2756 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7862.042 | 0.8929 | 0.8300 | 1.2756 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7863.018 | 1.0001 | 1.0001 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7863.018 | 1.0096 | 1.0092 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7863.018 | 0.9347 | 0.9365 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7863.018 | 1.0120 | 1.0115 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7863.018 | 0.8088 | 0.8073 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7863.018 | 1.0221 | 1.0210 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7863.018 | 1.0092 | 1.0088 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7863.018 | 0.9922 | 0.9925 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7863.018 | 0.9666 | 0.9678 | 2.0946 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7864.042 | 1.0445 | 1.0596 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7864.042 | 0.9602 | 0.9459 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7864.042 | 1.0397 | 1.0532 | 1.4812 | |
| Hs 578T | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7864.042 | 1.0388 | 1.0520 | 1.4812 |