Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9878.011 | 0.9874 | 0.9805 | 1.2938 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9878.011 | 0.7503 | 0.6017 | 1.2938 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9878.011 | 0.5136 | 0.1949 | 1.2938 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9878.011 | 0.0761 | -0.7267 | 1.2938 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9878.011 | 0.0462 | -0.8143 | 1.2938 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9889.021 | 0.9744 | 0.9633 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9889.021 | 1.0312 | 1.0443 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9889.021 | 0.9377 | 0.9103 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9889.021 | 1.0096 | 1.0136 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9889.021 | 0.9782 | 0.9688 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9889.021 | 0.7636 | 0.6499 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9889.021 | 0.4284 | 0.0923 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9889.021 | 0.0946 | -0.6283 | 1.4017 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9889.021 | 0.0477 | -0.7717 | 1.4017 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9033.075 | 0.9888 | 0.9765 | 0.9560 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9033.075 | 0.9947 | 0.9888 | 0.9560 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9033.075 | 0.9944 | 0.9882 | 0.9560 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9033.075 | 0.9800 | 0.9581 | 0.9560 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9033.075 | 0.9986 | 0.9970 | 0.9560 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9033.075 | 0.9951 | 0.9897 | 0.9560 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9033.075 | 0.8873 | 0.7649 | 0.9560 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9033.075 | 0.6699 | 0.3154 | 0.9560 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9033.075 | 0.3028 | -0.4269 | 0.9560 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9897.021 | 0.9941 | 0.9807 | 0.6103 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9897.021 | 1.0343 | 1.1137 | 0.6103 |