Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9897.021 | 1.0461 | 1.1531 | 0.6103 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9897.021 | 1.0149 | 1.0491 | 0.6103 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9897.021 | 1.0347 | 1.1151 | 0.6103 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9897.021 | 0.9715 | 0.9075 | 0.6103 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9897.021 | 0.7750 | 0.3171 | 0.6103 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9897.021 | 0.6039 | -0.1247 | 0.6103 | |
| T47D | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9897.021 | 0.2745 | -0.7595 | 0.6103 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9913.021 | 1.0622 | 1.3881 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9913.021 | 1.1528 | 2.0385 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9913.021 | 1.0520 | 1.3213 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9913.021 | 1.0376 | 1.2291 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9913.021 | 1.0734 | 1.4634 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9913.021 | 0.9395 | 0.6648 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9913.021 | 0.6285 | -0.4896 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9913.021 | 0.0721 | -0.9991 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9913.021 | 0.2556 | -0.9638 | 0.3401 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10150.021 | 1.0652 | 1.2761 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10150.021 | 1.1340 | 1.5874 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10150.021 | 0.9966 | 0.9860 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10150.021 | 1.0732 | 1.3112 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10150.021 | 1.0177 | 1.0732 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10150.021 | 0.9070 | 0.6376 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10150.021 | 0.5291 | -0.4569 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10150.021 | 0.0690 | -0.9916 | 0.4883 | |
| UACC-812 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10150.021 | 0.0482 | -0.9960 | 0.4883 |