Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7921.011 | 0.9391 | 0.8225 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7921.011 | 0.6019 | -0.0566 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7921.011 | 0.0623 | -0.9671 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10146.12 | 1.0231 | 1.0447 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10146.12 | 1.1379 | 1.2662 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10146.12 | 1.0703 | 1.1358 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10146.12 | 1.0118 | 1.0228 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 10146.12 | 1.0341 | 1.0658 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10146.12 | 0.9428 | 0.8892 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10146.12 | 0.9085 | 0.8228 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10146.12 | 0.4515 | -0.0731 | 1.0341 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10146.12 | 0.0390 | -0.9133 | 1.0341 | |
| SUM229PE | TNBC | - | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9860.011 | 1.1202 | 1.1614 | 1.4618 | |
| SUM229PE | TNBC | - | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9860.011 | 1.1828 | 1.2434 | 1.4618 | |
| SUM229PE | TNBC | - | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9860.011 | 1.1133 | 1.1524 | 1.4618 | |
| SUM229PE | TNBC | - | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9860.011 | 1.1834 | 1.2442 | 1.4618 | |
| SUM229PE | TNBC | - | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9860.011 | 1.2672 | 1.3518 | 1.4618 | |
| SUM229PE | TNBC | - | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9860.011 | 1.1756 | 1.2340 | 1.4618 | |
| SUM229PE | TNBC | - | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9860.011 | 0.6886 | 0.5494 | 1.4618 | |
| SUM229PE | TNBC | - | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9860.011 | 0.2574 | -0.2098 | 1.4618 | |
| SUM229PE | TNBC | - | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9860.011 | 0.2370 | -0.2532 | 1.4618 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9878.011 | 1.0262 | 1.0404 | 1.2938 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9878.011 | 1.2003 | 1.3031 | 1.2938 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9878.011 | 0.9880 | 0.9814 | 1.2938 | |
| SUM52PE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9878.011 | 1.1323 | 1.2016 | 1.2938 |